Communication: The Follow-Up of Biomarkers Better Predicts the Poor Outcome in COVID-19 Patients.
Ann Clin Lab Sci
; 50(6): 848-851, 2020 Nov.
Article
in English
| MEDLINE | ID: covidwho-984121
ABSTRACT
OBJECTIVE:
To investigate the course of biomarkers on admission and follow-up in order to identify early predictors for poor outcome in COVID-19 patients.METHODS:
In this study, 132 COVID-19 patients were classified as good outcome (n=62) and poor outcome (n=70) groups. Laboratory parameters were evaluated on admission and within 5-7 days after hospitalization.RESULTS:
Baseline levels of neutrophil-lymphocyte ratio, CRP, procalcitonin, ferritin, D-dimer and LDH were higher (p<0.01); lymphocyte count was lower in the poor outcome patients. During follow-up there was a larger decrease in lymphocyte count and more prominent increases in other biomarkers (p<0.001). In ROC analysis, the AUCs strongly indicated the poor outcome on days 5-7 of the hospitalization.CONCLUSIONS:
This study suggests that the follow-up measurements of the biomarkers better predict the poor outcome in COVID-19 pneumonia.Keywords
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Collection:
International databases
Database:
MEDLINE
Main subject:
Severity of Illness Index
/
Biomarkers
/
SARS-CoV-2
/
COVID-19
Type of study:
Cohort study
/
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
Ann Clin Lab Sci
Year:
2020
Document Type:
Article
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