Communication: Correlation of Point of Care SARS-CoV-2 Serological Assay with Quantitative ELISA.
Ann Clin Lab Sci
; 50(6): 852-854, 2020 Nov.
Article
in English
| MEDLINE | ID: covidwho-984501
ABSTRACT
Due to the COVID-19 pandemic, the Food and Drug Administration issued an Emergency Use Authorization to permit developers of certain serological tests to market their product prior to a comprehensive review. Nonetheless, the reliability of these assays is of great importance in order to be useful as a tool in estimating the relative proportions of different populations that have been exposed to SARS-CoV-2. We provide a sampling of 145 individuals from an ambulatory setting simultaneously tested with a qualitative point of care rapid finger prick Lateral Wave® IgM and IgG assay and a sample for the Mayo Clinic enzyme linked immunosorbent assay (ELISA) IgM/IgG antibody assay. Significant discrepancies did exist between the purported antibody responses as demonstrated by each assay.
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Collection:
International databases
Database:
MEDLINE
Main subject:
Immunoglobulin G
/
Immunoglobulin M
/
Enzyme-Linked Immunosorbent Assay
/
Point-of-Care Systems
/
SARS-CoV-2
/
COVID-19
/
Antibodies, Viral
Type of study:
Diagnostic study
/
Qualitative research
Limits:
Humans
Language:
English
Journal:
Ann Clin Lab Sci
Year:
2020
Document Type:
Article
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