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[COVID-19 and acute kidney injury in the intensive care unit]. / COVID-19 und akute Nierenschädigung im Intensivbereich.
Hardenberg, Jan-Hendrik B; Stockmann, Helena; Eckardt, Kai-Uwe; Schmidt-Ott, Kai M.
  • Hardenberg JB; Medizinische Klinik m. S. Nephrologie und Internistische Intensivmedizin, Charité - Unversitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Deutschland.
  • Stockmann H; Medizinische Klinik m. S. Nephrologie und Internistische Intensivmedizin, Charité - Unversitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Deutschland.
  • Eckardt KU; Medizinische Klinik m. S. Nephrologie und Internistische Intensivmedizin, Charité - Unversitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Deutschland.
  • Schmidt-Ott KM; Medizinische Klinik m. S. Nephrologie und Internistische Intensivmedizin, Charité - Unversitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Deutschland.
Nephrologe ; : 1-5, 2020 Dec 22.
Article in German | MEDLINE | ID: covidwho-986661
Semantic information from SemMedBD (by NLM)
1. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
2. Complication PROCESS_OF Patients
Subject
Complication
Predicate
PROCESS_OF
Object
Patients
3. risk factors PREDISPOSES Kidney Failure
Subject
risk factors
Predicate
PREDISPOSES
Object
Kidney Failure
4. Kidney Failur COEXISTS_WITH C5203670
Subject
Kidney Failur
Predicate
COEXISTS_WITH
Object
C5203670
5. Kidney Failur PROCESS_OF C0030705
Subject
Kidney Failur
Predicate
PROCESS_OF
Object
C0030705
6. Kidney Failur CAUSES C1561643
Subject
Kidney Failur
Predicate
CAUSES
Object
C1561643
7. Renal function PROCESS_OF Survivors
Subject
Renal function
Predicate
PROCESS_OF
Object
Survivors
8. COVID-19 COEXISTS_WITH Kidney Failure
Subject
COVID-19
Predicate
COEXISTS_WITH
Object
Kidney Failure
9. Thrombophilia COEXISTS_WITH COVID-19
Subject
Thrombophilia
Predicate
COEXISTS_WITH
Object
COVID-19
10. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
11. Complication PROCESS_OF Patients
Subject
Complication
Predicate
PROCESS_OF
Object
Patients
12. risk factors PREDISPOSES Kidney Failure
Subject
risk factors
Predicate
PREDISPOSES
Object
Kidney Failure
13. Kidney Failure, Acute COEXISTS_WITH COVID-19
Subject
Kidney Failure, Acute
Predicate
COEXISTS_WITH
Object
COVID-19
14. Kidney Failure, Acute PROCESS_OF Patients
Subject
Kidney Failure, Acute
Predicate
PROCESS_OF
Object
Patients
15. Kidney Failure, Acute CAUSES Chronic Kidney Diseases
Subject
Kidney Failure, Acute
Predicate
CAUSES
Object
Chronic Kidney Diseases
16. Renal function PROCESS_OF Survivors
Subject
Renal function
Predicate
PROCESS_OF
Object
Survivors
17. COVID-19 COEXISTS_WITH Kidney Failure
Subject
COVID-19
Predicate
COEXISTS_WITH
Object
Kidney Failure
18. Thrombophilia COEXISTS_WITH COVID-19
Subject
Thrombophilia
Predicate
COEXISTS_WITH
Object
COVID-19
ABSTRACT
Acute kidney injury (AKI) is a frequent and severe complication in coronavirus disease 2019 (COVID-19) patients in the intensive care unit. The development of COVID-19 associated AKI is closely linked to the severity of the disease course. The main risk factor for kidney failure requiring kidney replacement therapy is the necessity for invasive ventilation, whereby the onset of renal failure is often closely associated with the timing of intubation. Additionally, the risk factors for a severe course of COVID-19 have been shown to also be risk factors for renal failure. AKI in COVID-19 shows a high mortality and in some patients leads to chronic kidney disease; however, full recovery of kidney function in survivors who need dialysis is not uncommon. With respect to prevention and treatment of renal failure associated with COVID-19, the same recommendations as for AKI from other causes are valid (Kidney Disease Improving Global Outcomes, KDIGO bundles). Due to the large numbers of patients in the setting of overwhelmed resources, the availability of extracorporeal renal replacement procedures can become critical, especially since hypercoagulation is frequent in COVID­19. In order to avoid triage situations, in some centers acute peritoneal dialysis was used as an alternative to extracorporeal procedures.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Clinical Practice Guide / Risk factors Language: German Journal: Nephrologe Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Clinical Practice Guide / Risk factors Language: German Journal: Nephrologe Year: 2020 Document Type: Article