Widespread sensory neuropathy in diabetic patients hospitalized with severe COVID-19 infection.
Diabetes Res Clin Pract
; 172: 108631, 2021 Feb.
Article
in English
| MEDLINE | ID: covidwho-987443
ABSTRACT
AIMS:
To characterize the distribution and severity of sensory neuropathy using a portable quantitative sensory testing (QST) device in diabetic patients (DM) hospitalized with severe COVID-19 infection.METHODS:
Four patients with diabetes and severe SARS-CoV-2 requiring non-invasive ventilation for a protracted duration underwent clinical, laboratory and radiologic assessment and detailed evaluation of neuropathic symptoms, neurological assessment, QST on the dorsum of the foot and face using NerveCheck Master with assessment of taste and smell.RESULTS:
All four subjects developed neuropathic symptoms characterized by numbness in the feet with preserved reflexes. QST confirmed symmetrical abnormality of vibration and thermal thresholds in both lower limbs in all patients and an abnormal heat pain threshold on the face of two patients and altered taste and smell.CONCLUSIONS:
Severe COVID-19 infection with hypoxemia is associated with neuropathic symptoms and widespread sensory dysfunction in patients with DM.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Sensory Thresholds
/
Sensation Disorders
/
Diabetes Mellitus
/
Diabetic Neuropathies
/
SARS-CoV-2
/
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
Diabetes Res Clin Pract
Journal subject:
Endocrinology
Year:
2021
Document Type:
Article
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