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Posterior reversible encephalopathy syndrome and COVID-19: A series of 6 cases from Lombardy, Italy.
Colombo, Antonio; Martinelli Boneschi, Filippo; Beretta, Sandro; Bresolin, Nereo; Versino, Maurizio; Lorusso, Lorenzo; Spagnoli, Diego; Nastasi, Giulia; Vallauri, Davide; Rota, Stefania; Repaci, Maria; Ferrarini, Massimo; Pozzato, Mattia; Princiotta Cariddi, Lucia; Tabaee Damavandi, Payam; Carimati, Federico; Banfi, Paola; Clemenzi, Alessandro; Marelli, Margherita; Giorgianni, Andrea; Vinacci, Gabriele; Mauri, Marco; Melzi, Paola; Di Stefano, Maria; Tetto, Antonio; Canesi, Margherita; Salmaggi, Andrea.
  • Colombo A; SNO (Society of Hospital Neurosciences, Italy) and Polo Neurologico Brianteo, Seregno, MB, Italy.
  • Martinelli Boneschi F; Dino Ferrari Centre, Department of Pathophysiology and Transplantation (DEPT), University of Milan and IRCCS Ca' Granda Foundation Ospedale Maggiore Policlinico, Neurology Unit and MS Center Milan, Italy.
  • Beretta S; Neurology and Stroke Unit, Radiology Unity, ASST Vimercate (MB), Italy.
  • Bresolin N; Dino Ferrari Centre, Department of Pathophysiology and Transplantation (DEPT), University of Milan and IRCCS Ca' Granda Foundation Ospedale Maggiore Policlinico, Neurology Unit and MS Center Milan, Italy.
  • Versino M; University of Insubria, Clinical and Experimental Medicine and Medical Humanitates, Center of Research in Medical Pharmacology, Neurology and Stroke Unit, Neuroradiology, Pneumology ASST Sette Laghi, Varese, Italy.
  • Lorusso L; Neurology and Stroke Unit Merate Hospital, ASST, Lecco, Italy.
  • Spagnoli D; Neurosurgery and Neurorehabilitation Gravedona Hospital, Como, Italy.
  • Nastasi G; Neurology and Stroke Unit, Radiology Unity, ASST Vimercate (MB), Italy.
  • Vallauri D; Neurology and Stroke Unit, Radiology Unity, ASST Vimercate (MB), Italy.
  • Rota S; Neurology and Stroke Unit, Radiology Unity, ASST Vimercate (MB), Italy.
  • Repaci M; Neurology and Stroke Unit, Radiology Unity, ASST Vimercate (MB), Italy.
  • Ferrarini M; Neurology and Stroke Unit, Radiology Unity, ASST Vimercate (MB), Italy.
  • Pozzato M; Dino Ferrari Centre, Department of Pathophysiology and Transplantation (DEPT), University of Milan and IRCCS Ca' Granda Foundation Ospedale Maggiore Policlinico, Neurology Unit and MS Center Milan, Italy.
  • Princiotta Cariddi L; University of Insubria, Clinical and Experimental Medicine and Medical Humanitates, Center of Research in Medical Pharmacology, Neurology and Stroke Unit, Neuroradiology, Pneumology ASST Sette Laghi, Varese, Italy.
  • Tabaee Damavandi P; University of Insubria, Clinical and Experimental Medicine and Medical Humanitates, Center of Research in Medical Pharmacology, Neurology and Stroke Unit, Neuroradiology, Pneumology ASST Sette Laghi, Varese, Italy.
  • Carimati F; University of Insubria, Clinical and Experimental Medicine and Medical Humanitates, Center of Research in Medical Pharmacology, Neurology and Stroke Unit, Neuroradiology, Pneumology ASST Sette Laghi, Varese, Italy.
  • Banfi P; University of Insubria, Clinical and Experimental Medicine and Medical Humanitates, Center of Research in Medical Pharmacology, Neurology and Stroke Unit, Neuroradiology, Pneumology ASST Sette Laghi, Varese, Italy.
  • Clemenzi A; University of Insubria, Clinical and Experimental Medicine and Medical Humanitates, Center of Research in Medical Pharmacology, Neurology and Stroke Unit, Neuroradiology, Pneumology ASST Sette Laghi, Varese, Italy.
  • Marelli M; University of Insubria, Clinical and Experimental Medicine and Medical Humanitates, Center of Research in Medical Pharmacology, Neurology and Stroke Unit, Neuroradiology, Pneumology ASST Sette Laghi, Varese, Italy.
  • Giorgianni A; University of Insubria, Clinical and Experimental Medicine and Medical Humanitates, Center of Research in Medical Pharmacology, Neurology and Stroke Unit, Neuroradiology, Pneumology ASST Sette Laghi, Varese, Italy.
  • Vinacci G; University of Insubria, Clinical and Experimental Medicine and Medical Humanitates, Center of Research in Medical Pharmacology, Neurology and Stroke Unit, Neuroradiology, Pneumology ASST Sette Laghi, Varese, Italy.
  • Mauri M; University of Insubria, Clinical and Experimental Medicine and Medical Humanitates, Center of Research in Medical Pharmacology, Neurology and Stroke Unit, Neuroradiology, Pneumology ASST Sette Laghi, Varese, Italy.
  • Melzi P; Neurology and Stroke Unit Merate Hospital, ASST, Lecco, Italy.
  • Di Stefano M; Neurology and Stroke Unit Merate Hospital, ASST, Lecco, Italy.
  • Tetto A; Neurology and Stroke Unit Merate Hospital, ASST, Lecco, Italy.
  • Canesi M; Neurosurgery and Neurorehabilitation Gravedona Hospital, Como, Italy.
  • Salmaggi A; Neurology and Stroke Unit ASST, Lecco, Italy.
eNeurologicalSci ; 22: 100306, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-987639
ABSTRACT
Posterior reversible encephalopathy cases are increasingly being reported in patients affected by COVID-19, but the largest series so far only includes 4 patients. We present a series of 6 patients diagnosed with PRES during COVID-19 hospitalized in 5 Centers in Lombardia, Italy. 5 out of the 6 patients required intensive care assistence and seizures developed at weaning from assisted ventilation. 3 out of 6 patients underwent cerebrospinal fluid analysis which was normal in all cases, with negative PCR for Sars-CoV-2 genome search. PRES occurrence may be less rare than supposed in COVID-19 patients and a high suspicion index is warranted for prompt diagnosis and treatment.
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Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: ENeurologicalSci Year: 2021 Document Type: Article Affiliation country: J.ensci.2020.100306

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Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: ENeurologicalSci Year: 2021 Document Type: Article Affiliation country: J.ensci.2020.100306