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Clinical and Demographic Characteristics of COVID-19 patients in Lagos, Nigeria: A Descriptive Study.
Otuonye, Ngozi Mirabel; Olumade, Testimony Jesupamilerin; Ojetunde, Mercy Mayowa; Holdbrooke, Susan Abba; Ayoola, Joy Boluwatife; Nyam, Itse Yusuf; Iwalokun, Bamidele; Onwuamah, Chika; Uwandu, Mabel; Abayomi, Akinola; Osibogun, Akin; Bowale, Abimbola; Osikomaiya, Bodunrin; Thomas, Babafemi; Mutiu, Bamidele; Odunukwe, Nkiruka Nnonyelum.
  • Otuonye NM; Central Research Laboratory, Nigerian Institute of Medical Research, Yaba, Lagos. Electronic address: mnotuonye@gmail.com.
  • Olumade TJ; Department of Biological Sciences, Redeemer's University, Ede, Osun state; African Centre of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Osun state.
  • Ojetunde MM; Central Research Laboratory, Nigerian Institute of Medical Research, Yaba, Lagos.
  • Holdbrooke SA; Central Research Laboratory, Nigerian Institute of Medical Research, Yaba, Lagos.
  • Ayoola JB; Central Research Laboratory, Nigerian Institute of Medical Research, Yaba, Lagos.
  • Nyam IY; Central Research Laboratory, Nigerian Institute of Medical Research, Yaba, Lagos.
  • Iwalokun B; Molecular Biological and Biotechnology Department, Nigerian Institute of Medical Research, Yaba, Lagos.
  • Onwuamah C; Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos.
  • Uwandu M; Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos.
  • Abayomi A; Lagos State Ministry of Health, Alausa, Ikeja, Lagos, Nigeria.
  • Osibogun A; College of Medicine University of Lagos, Nigeria; Lagos State Primary Health Care Board, Lagos, Nigeria.
  • Bowale A; Mainland Infectious Disease Hospital, Yaba, Lagos.
  • Osikomaiya B; Mainland Infectious Disease Hospital, Yaba, Lagos.
  • Thomas B; Mainland Infectious Disease Hospital, Yaba, Lagos.
  • Mutiu B; Mainland Infectious Disease Hospital, Yaba, Lagos.
  • Odunukwe NN; Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos.
J Natl Med Assoc ; 113(3): 301-306, 2021 Jun.
Article in English | MEDLINE | ID: covidwho-988462
Preprint
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Semantic information from SemMedBD (by NLM)
1. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
2. Disease PROCESS_OF Patients
Subject
Disease
Predicate
PROCESS_OF
Object
Patients
3. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
4. Disease PROCESS_OF Patients
Subject
Disease
Predicate
PROCESS_OF
Object
Patients
ABSTRACT

INTRODUCTION:

COVID-19 is an emerging, rapidly evolving global situation, infecting over 25 million people and causing more than 850,000 deaths. Several signs and symptoms have been described to be characteristic of the disease. However, there is a dearth of report on the description of the clinical characteristics of the disease in patients from Nigeria. This study was designed to provide a description of the clinical and demographic characteristics of COVID-19 patients in Nigeria.

METHODS:

This study is a case series that includes patients that are evaluated between May and August 2020, and diagnosed with COVID-19. Patient health records were reviewed and evaluated to describe the clinical characteristics on presentation.

RESULTS:

A total of 154 COVID-19 patients were included in this study, with a mean age (S.D.) of 46.16 (13.701). Most of the patients survived (mortality rate of 2.6%), and were symptomatic (89.6%). There were more males (74.7%) than females, and the most common symptoms were fever, breathing difficulty, dry cough and malaise. Co-morbidities were also present in almost half of the study participants (49.4%).

CONCLUSION:

This study presents the most extensive description, to date, on the clinical and demographic characteristics of COVID-19 patients in Nigeria. Males are more likely than females to be infected with COVID-19 and the most occurring symptoms are fever, breathing difficulty, malaise, dry cough and chest pain. Old age and the presence of co-morbidities may also be associated with developing the severe disease.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / COVID-19 Type of study: Risk factors Limits: Female / Humans / Male / Middle aged Country/Region as subject: Africa Language: English Journal: J Natl Med Assoc Year: 2021 Document Type: Article

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / COVID-19 Type of study: Risk factors Limits: Female / Humans / Male / Middle aged Country/Region as subject: Africa Language: English Journal: J Natl Med Assoc Year: 2021 Document Type: Article