Life-Threatening COVID-19: Defective Interferons Unleash Excessive Inflammation.
Med (N Y)
; 1(1): 14-20, 2020 12 18.
Article
in English
| MEDLINE | ID: covidwho-988793
ABSTRACT
The risk of life-threatening COVID-19 pneumonia increases sharply after 65 years of age, but other epidemiological risk factors, genetic or otherwise, are modest. Various rare monogenic inborn errors of type I interferons (IFNs) underlie critical disease, and neutralizing autoantibodies against type I IFNs account for at least 10% of critical cases.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Interferon Type I
/
COVID-19
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Med (N Y)
Year:
2020
Document Type:
Article
Affiliation country:
J.medj.2020.12.001
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