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Childhood vaccinations: Hidden impact of COVID-19 on children in Singapore.
Zhong, Youjia; Clapham, Hannah Eleanor; Aishworiya, Ramkumar; Chua, Ying Xian; Mathews, Jancy; Ong, Mabel; Wang, Jingji; Murugasu, Belinda; Chiang, Wen Chin; Lee, Bee Wah; Chin, Hui-Lin.
  • Zhong Y; Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore.
  • Clapham HE; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
  • Aishworiya R; Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore. Electronic address: aishworiya_ramkumar@nuhs.edu.sg.
  • Chua YX; National University Polyclinics, Singapore.
  • Mathews J; National University Polyclinics, Singapore.
  • Ong M; National University Polyclinics, Singapore.
  • Wang J; Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore.
  • Murugasu B; Mount Elizabeth Medical Centre, Singapore.
  • Chiang WC; Mount Elizabeth Medical Centre, Singapore.
  • Lee BW; Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Chin HL; Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore.
Vaccine ; 39(5): 780-785, 2021 01 29.
Article in English | MEDLINE | ID: covidwho-989367
ABSTRACT
Although the direct health impact of Coronavirus disease (COVID-19) pandemic on child health is low, there are indirect impacts across many aspects. We compare childhood vaccine uptake in three types of healthcare facilities in Singapore - public primary care clinics, a hospital paediatric unit, and private paediatrician clinics - from January to April 2020, to baseline, and calculate the impact on herd immunity for measles. We find a 25.6% to 73.6% drop in Measles-Mumps-Rubella (MMR) uptake rates, 0.4 - 10.3% drop for Diphtheria-Tetanus-Pertussis-inactivated Polio-Haemophilus influenza (5-in-1), and 8.0-67.8% drop for Pneumococcal conjugate vaccine (PCV) across all 3 sites. Consequent herd immunity reduces to 74-84% among 12-month- to 2-year-olds, well below the 95% coverage that is protective for measles. This puts the whole community at risk for a measles epidemic. Public health efforts are urgently needed to maintain efficacious coverage for routine childhood vaccines during the COVID-19 pandemic.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Public Health / Child Health / Vaccination Coverage / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Child, preschool / Humans / Infant Country/Region as subject: Asia Language: English Journal: Vaccine Year: 2021 Document Type: Article Affiliation country: J.vaccine.2020.12.054

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Public Health / Child Health / Vaccination Coverage / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Child, preschool / Humans / Infant Country/Region as subject: Asia Language: English Journal: Vaccine Year: 2021 Document Type: Article Affiliation country: J.vaccine.2020.12.054