The association of oxygen saturation, tomography findings and D-dimer levels in coronavirus disease 2019 patients.
Blood Coagul Fibrinolysis
; 31(8): 558-561, 2020 Dec.
Article
in English
| MEDLINE | ID: covidwho-990910
ABSTRACT
Coronavirus disease is a highly contagious disease caused by systemic acute respiratory syndrome coronavirus 2 with high mortality rates. We aimed to evaluate the relationship between serum D-dimer levels and tomography findings at the time of admission in patients diagnosed with coronavirus disease 2019 (COVID-19). This study included 94 patients, 48 women (51%) and 46 men (49%), diagnosed by PCR method. Patients without any suspicious findings on thorax tomography and having oxygen saturation above 90% at the time of presentation were included as the first group. Patients with suspicious tomography findings but having oxygen saturation above 90% were designed as the second group, and patients with both suspicious tomography findings for COVID-19 and low oxygen saturation levels (<90%) at the time of admission were taken as the third group. Patients with oxygen desaturation were significantly older than the patients with normal oxygen saturations (Pâ=â0.001). Patients with thorax tomography findings were having significantly higher D-dimer levels (Pâ=â0.001). Patients with oxygen desaturation were having significantly higher D-dimer levels than the patients with normal oxygen saturations (Pâ=â0.001). There was a significant negative correlation between oxygen saturation and D-dimer levels in all patients with and without tomography findings (râ=â-0.301, Pâ=â0.016). Similarly, there was a significant positive correlation between the oxygen saturation and the lymphocyte count (râ=â0.300, Pâ<â0.017). Thorax tomography and D-dimer levels significantly correlate in patients with suspected COVID-19 admission. It should be kept in mind that patients with low oxygen saturation and high D-dimer levels may have serious lung involvement.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Oxygen
/
Pneumonia, Viral
/
Fibrin Fibrinogen Degradation Products
/
Tomography, X-Ray Computed
/
Coronavirus Infections
/
Betacoronavirus
Type of study:
Experimental Studies
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
Blood Coagul Fibrinolysis
Journal subject:
Vascular Diseases
/
Hematology
Year:
2020
Document Type:
Article
Affiliation country:
MBC.0000000000000964
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