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Comparison of clinical, laboratory, and radiological characteristics between SARS-CoV-2 infection and community-acquired pneumonia caused by influenza virus: A cross-sectional retrospective study.
Lin, Yi-Hua; Luo, Wen; Wu, Ding-Hui; Lu, Fang; Hu, Su-Xian; Yao, Xiang-Yang; Wang, Zhan-Xiang; Shi, Yong-Hong.
  • Lin YH; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Xiamen University, Xiamen.
  • Luo W; Department of Clinical Medicine, Fujian Medical University.
  • Wu DH; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Xiamen University, Xiamen.
  • Lu F; Department of pulmonary diseases, the First Affiliated Hospital of Xiamen University.
  • Hu SX; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Xiamen University, Xiamen.
  • Yao XY; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Xiamen University, Xiamen.
  • Wang ZX; Department of pulmonary diseases, the First Affiliated Hospital of Xiamen University.
  • Shi YH; Department of Clinical Medicine, Fujian Medical University.
Medicine (Baltimore) ; 99(44): e23064, 2020 Oct 30.
Article in English | MEDLINE | ID: covidwho-990918
ABSTRACT
Coronavirus disease 2019 (COVID-19) is the most important global public health issue that we currently face. We aimed to explore the clinical features of patients with COVID-19 and compared them with those of hospitalized community-acquired pneumonia (CAP) patients caused by influenza virus during the same period.From Jan 1, to Mar 4, 2020, patients with COVID-19 or CAP caused by influenza virus who were admitted to the First Affiliated Hospital of Xiamen University were consecutively screened for enrollment.A total of 35 COVID-19 patients and 22 CAP patients caused by influenza virus were included in this study. Most of COVID-19 patients had characteristics of familial clustering (63%), however, in the other group, there was no similar finding. The percentages of patients with a high fever (the highest recorded temperature was ≥39.0°C; 11% vs 45% [COVID-19 vs CAP groups, respectively]), dyspnea (9% vs 59%), leukocytosis (3% vs 32%), elevated C-reactive protein concentrations (>10 mg/L, 48% vs 86%), elevated procalcitonin levels (>0.1 ng/ml, 15% vs 73%), PaO2/FiO2 <200 mm Hg (4% vs 22%), and infiltration on imaging (29% vs 68%) in the COVID-19 group were less than those same indices in the hospitalized CAP patients caused by influenza virus. Ground-glass opacity with reticular pattern (63%) and interlobular septal thickening (71%) in chest CT were commonly observed in the COVID-19 group.COVID-19 and CAP caused by influenza virus appear to share some similarities in clinical manifestaions but they definitely have major distinctions. Influenza infection remains a health problem even during COVID-19 pandemic.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Influenza, Human Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Medicine (Baltimore) Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Influenza, Human Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Medicine (Baltimore) Year: 2020 Document Type: Article