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SARS-CoV-2 not found in pressure injury exudates from COVID-19 patients.
Yu, Nanze; Zhang, Yuwei; Xiao, Meng; Cao, Wei; Zhang, Yan; Yang, Yang; Liu, Zhengyin; Li, Yunzhu; Long, Xiao; Liu, Zhifei; Zhang, Shuyang; Wang, Xiaojun.
  • Yu N; Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Zhang Y; Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Xiao M; Department of Laboratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Cao W; Department of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Zhang Y; Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Yang Y; Department of Orthopaedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Liu Z; Department of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Li Y; Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Long X; Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Liu Z; Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Zhang S; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Wang X; Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
J Cosmet Dermatol ; 20(2): 372-380, 2021 Feb.
Article in English | MEDLINE | ID: covidwho-991566
ABSTRACT

BACKGROUND:

The emergence of COVID-19 has become a global health emergency. The transmissibility of the disease is of great interest to healthcare workers and scientists alike. The primary route of transmission is via respiratory droplets, but viral RNA has also been found in feces and body fluids such as urine, serum, and semen. So far, there has been no report on whether SARS-CoV-2 is present in the exudates of cutaneous lesions. This study was designed to investigate whether SARS-CoV-2 can be found in the pressure injury exudates in patients with severe COVID-19 infections.

METHODS:

46 critically ill COVID-19 patients who were admitted to the ICU of the Sino-French New City Branch of Tongji Hospital in Wuhan between February 4 and April 12 developed pressure injuries. 22 patients with pressure injuries had wound exudates. Wound and pharyngeal swabs of the 22 patients were collected and RT-PCRs were conducted to detect SARS-CoV-2 viral RNA.

RESULTS:

At the time of pressure injury, 5 patients still tested positive by pharyngeal swabs, the rest of the 17 patients tested negative. However, none of the wound exudate swabs from the participants tested positive for SARS-CoV-2 by RT-PCR.

CONCLUSION:

Our study suggests that it is rather unlikely that COVID-19 can be transmitted via pressure injury exudates, but we still recommend standardized personal protective equipment, face shield and an additional pair of gloves when treating pressure injuries.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pressure Ulcer / Exudates and Transudates / SARS-CoV-2 / COVID-19 Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: J Cosmet Dermatol Journal subject: Dermatology Year: 2021 Document Type: Article Affiliation country: Jocd.13887

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pressure Ulcer / Exudates and Transudates / SARS-CoV-2 / COVID-19 Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: J Cosmet Dermatol Journal subject: Dermatology Year: 2021 Document Type: Article Affiliation country: Jocd.13887