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Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three Cases.
Pal, Chaitanya; Przydzial, Paulina; Chika-Nwosuh, Ogechukwu; Shah, Shrey; Patel, Pratik; Madan, Nikhil.
  • Pal C; Department of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USA.
  • Przydzial P; Department of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USA.
  • Chika-Nwosuh O; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USA.
  • Shah S; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USA.
  • Patel P; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USA.
  • Madan N; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USA.
Case Rep Pulmonol ; 2020: 8849068, 2020.
Article in English | MEDLINE | ID: covidwho-991972
ABSTRACT
Bacterial coinfections are not uncommon with respiratory viral pathogens. These coinfections can add to significant mortality and morbidity. We are currently dealing with the SARS-CoV-2 pandemic, which has affected over 15 million people globally with over half a million deaths. Previous respiratory viral pandemics have taught us that bacterial coinfections can lead to higher mortality and morbidity. However, there is limited literature on the current SARS-CoV-2 pandemic and associated coinfections, which reported infection rates varying between 1% and 8% based on various cross-sectional studies. In one meta-analysis of coinfections in COVID-19, rates of Streptococcus pneumoniae coinfections have been negligible when compared to previous influenza pandemics. Current literature does not favor the use of empiric, broad-spectrum antibiotics in confirmed SARS-CoV-2 infections. We present three cases of confirmed SARS-CoV-2 infections complicated by Streptococcus pneumoniae coinfection. These cases demonstrate the importance of concomitant testing for common pathogens despite the need for antimicrobial stewardship.

Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Observational study / Randomized controlled trials / Reviews Language: English Journal: Case Rep Pulmonol Year: 2020 Document Type: Article Affiliation country: 2020

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Observational study / Randomized controlled trials / Reviews Language: English Journal: Case Rep Pulmonol Year: 2020 Document Type: Article Affiliation country: 2020