Your browser doesn't support javascript.
Correlation of the renal function changes to prognosis in critical patients with COVID-19
Medical Journal of Chinese People's Liberation Army ; 45(11):1156-1160, 2020.
Article in Chinese | EMBASE | ID: covidwho-994247
ABSTRACT

Objective:

To get the message of kidney injury and its causes in patients with COVID-19, and analyze the correlation of kidney injury to COVID-19 typing and prognosis, so provide a reference for the treatment and prognosis evaluation of COVID-19.

Methods:

According to the retrospective cohort study protocol, the clinical data and prognosis of 319 confirmed patients with COVID-19, admitted in the General Hospital of Central Theater Command (Wuhan) from Jan. 1st to Mar. 14th, 2020, were collected. The correlation of COVID-19 patients' renal function changes to the classification and prognosis of diseases were analyzed using univariate and multivariate logistic regression analysis.

Results:

The mean age of the 319 confirmed patients with COVID-19 was (55.2±17.0) years. The proportion of non-critical group (mild+moderate type) and critical group (severe+critical type) were 62.1% (198/319) and 37.9% (121/319), respectively. The fatality rate of present study cohort was 5.6% (18/319). About 3.8% cases (12/319) were with elevated blood urea nitrogen (BUN) and serum creatinine (SCr) at admission, and about 5.6% cases (18/319) were with elevated BUN only at admission. Univariate logistic regression analysis revealed that the age, the levels of SCr and BUN at admission and one week after admission, the combination of diabetes mellitus, and chronic kidney disease were the risk factors associated with the death in critical group patients (P<0.05). Multivariate logistic regression analysis revealed that the elevated levels of BUN at admission and one week after admission were the independent risk factors of death in the critical group patients.

Conclusions:

The elevated levels of BUN at admission and one week after admission were the important clinical features and independent risk factors associated with the death of critical COVID-19 patients. More attention should be paid to all kinds of clinical factors that may lead to increase the level of BUN.

Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Prognostic study Language: Chinese Journal: Medical Journal of Chinese People's Liberation Army Year: 2020 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Prognostic study Language: Chinese Journal: Medical Journal of Chinese People's Liberation Army Year: 2020 Document Type: Article