[Formation of population gene pools of zoonotic viruses, potentially threatening biosafety].
Vopr Virusol
; 65(5): 243-258, 2020 11 14.
Article
in Russian
| MEDLINE | ID: covidwho-995272
ABSTRACT
The possible formation of population gene pools of zoonotic viruses with a respiratory route of transmission and a possibility of a pandemic at different stages of biosphere evolution is analyzed. Forming of Poxviruses (Entomopoxvirinae) gene pool could be the beginning of transformation from Plants to Arthropoda (Carbon - 375 million years ago) with further evolution connected with Rodentia (Pliocene - 75-70 million years ago) and further separation of genera (500-300 thousand years ago), and respiratory transmission (epidemics) between humans (10-2 thousand years BC). Smallpox comeback would be possible. Orthomyxoviruses relicts (genus Isavirus) were possibly connected with Ichthya (Silurian - 500-410 million years ago), and then close interaction with Aves (the Cretaceous, 125-110 million years ago) with the division of genera and respiratory transmission (epidemics) between humans (10-2 thousand BC). Next pandemic of influenza A could be catastrophic in terms of the number of victims and economic damage.Coronaviruses formed a gene pool by interaction with Amphibia (subfamily Letovirinae) and then with Chiroptera in Tertiary (110-75 million years ago) with transformation to Artiodactyla (Eocene - 70-60 million years ago), and only 10-2 thousand years BC acquired the ability to a respiratory transmission and became Alphaviruses, a seasonal infection of humans. A similar situation is possible in the near future with SARS-CoV-2. Pandemics associated with zoonoses even more serious than COVID-19 are likely. Constant monitoring of populational gene pools of zoonotic viruses is necessary.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Disease Reservoirs
/
Zoonoses
/
Evolution, Molecular
/
Gene Pool
/
SARS-CoV-2
/
COVID-19
Type of study:
Observational study
Limits:
Animals
/
Humans
Language:
Russian
Journal:
Vopr Virusol
Year:
2020
Document Type:
Article
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