BMI as a Risk Factor for Clinical Outcomes in Patients Hospitalized with COVID-19 in New York.
Obesity (Silver Spring)
; 29(2): 279-284, 2021 02.
Article
in English
| MEDLINE | ID: covidwho-996269
ABSTRACT
OBJECTIVE:
This study examined the association between BMI and clinical outcomes among patients with coronavirus disease 2019 (COVID-19) infection.METHODS:
A total of 10,861 patients with COVID-19 infection who were admitted to the Northwell Health system hospitals between March 1, 2020, and April 27, 2020, were included in this study. BMI was classified as underweight, normal weight, overweight, and obesity classes I, II, and III. Primary outcomes were invasive mechanical ventilation (IMV) and death.RESULTS:
A total of 243 (2.2%) patients were underweight, 2,507 (23.1%) were normal weight, 4,021 (37.0%) had overweight, 2,345 (21.6%) had obesity class I, 990 (9.1%) had obesity class II, and 755 (7.0%) had obesity class III. Patients who had overweight (odds ratio [OR] = 1.27 [95% CI 1.11-1.46]), obesity class I (OR = 1.48 [95% CI 1.27-1.72]), obesity class II (OR = 1.89 [95% CI 1.56-2.28]), and obesity class III (OR = 2.31 [95% CI 1.88-2.85]) had an increased risk of requiring IMV. Underweight and obesity classes II and III were statistically associated with death (OR = 1.44 [95% CI 1.08-1.92]; OR = 1.25 [95% CI 1.03-1.52]; OR = 1.61 [95% CI 1.30-2.00], respectively). Among patients who were on IMV, BMI was not associated with inpatient deaths.CONCLUSIONS:
Patients who are underweight or who have obesity are at risk for mechanical ventilation and death, suggesting that pulmonary complications (indicated by IMV) are a significant contributor for poor outcomes in COVID-19 infection.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Thinness
/
Body Mass Index
/
Overweight
/
COVID-19
/
Hospitalization
Type of study:
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
North America
Language:
English
Journal:
Obesity (Silver Spring)
Journal subject:
Nutritional Sciences
/
Physiology
/
Metabolism
Year:
2021
Document Type:
Article
Affiliation country:
Oby.23076
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