Your browser doesn't support javascript.
The role of biomaterials and three dimensional (3D) in vitro tissue models in fighting against COVID-19.
Seyfoori, Amir; Amereh, Meitham; Dabiri, Seyed Mohammad Hossein; Askari, Esfandyar; Walsh, Tavia; Akbari, Mohsen.
  • Seyfoori A; Laboratory for Innovations in Micro Engineering (LiME), Department of Mechanical Engineering, University of Victoria, Victoria, Canada. makbari@uvic.ca amirseyfoori@uvic.ca.
Biomater Sci ; 9(4): 1217-1226, 2021 Feb 21.
Article in English | MEDLINE | ID: covidwho-997953
Semantic information from SemMedBD (by NLM)
1. Pandemics CAUSES Communicable Diseases
Subject
Pandemics
Predicate
CAUSES
Object
Communicable Diseases
2. Pandemics CAUSES Communicable Diseases
Subject
Pandemics
Predicate
CAUSES
Object
Communicable Diseases
ABSTRACT
Over the past century, viral respiratory pandemics have been a leading cause of infectious disease worldwide. A deep understanding of the underlying mechanisms of the viral interactions with host cells at the target sites is necessary for a rapid response to such pandemics. To meet this aim, various testing platforms are required to recapitulate the pathophysiological behavior of the virus within the respiratory tract. These bioengineered platforms can effectively be used for the development of different therapeutics and vaccines. This paper briefly reviews the progress in the areas of biomaterial use for pulmonary tissue regeneration and integration with current bioengineered platforms including engineered tissues, organoids, and organs-on-a-chip platforms for viral respiratory disease studies. Finally, a brief overview of the opportunities presented by organ-on-a-chip systems for studying COVID-19 and subsequent drug development is introduced.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Biocompatible Materials / Tissue Engineering / SARS-CoV-2 / COVID-19 / Models, Biological Limits: Animals / Humans Language: English Journal: Biomater Sci Year: 2021 Document Type: Article

Full text: Available Collection: International databases Database: MEDLINE Main subject: Biocompatible Materials / Tissue Engineering / SARS-CoV-2 / COVID-19 / Models, Biological Limits: Animals / Humans Language: English Journal: Biomater Sci Year: 2021 Document Type: Article