Hypercoagulopathy in Severe COVID-19: Implications for Acute Care.
Thromb Haemost
; 120(12): 1654-1667, 2020 Dec.
Article
in English
| MEDLINE | ID: covidwho-998022
ABSTRACT
COVID-19 was first described in late 2019 and has since developed into a pandemic affecting more than 21 million people worldwide. Of particular relevance for acute care is the occurrence of COVID-19-associated coagulopathy (CAC), which is characterised by hypercoagulability, immunothrombosis and venous thromboembolism, and contributes to hypoxia in a significant proportion of patients. This review describes diagnosis and treatment of CAC in the emergency department and in intensive care. We summarise the pathological mechanisms and common complications of CAC such as pulmonary thrombosis and venous thromboembolic events and discuss current strategies for thromboprophylaxis and therapeutic anti-coagulation in the acute care setting.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Venous Thromboembolism
/
SARS-CoV-2
/
COVID-19
/
Lung
/
Anticoagulants
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Animals
/
Humans
Language:
English
Journal:
Thromb Haemost
Year:
2020
Document Type:
Article
Affiliation country:
S-0040-1721487
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