Acute Corneal Endothelial Graft Rejection With Coinciding COVID-19 Infection.
Cornea
; 40(1): 123-124, 2021 Jan.
Article
in English
| MEDLINE | ID: covidwho-998523
ABSTRACT
PURPOSE:
To report a case of acute corneal endothelial graft rejection with the concurrent onset of coronavirus disease 2019 (COVID-19) symptoms.METHODS:
Case report.RESULTS:
A 31-year-old African American woman with a history of asthma, sleep apnea, obesity (body mass index of 40), and bilateral keratoconus was noted to have acute corneal endothelial graft rejection 3 months after uncomplicated penetrating keratoplasty of the left eye. The patient developed dysgeusia and subjective fever on the same day as ocular discomfort, and she was subsequently diagnosed with COVID-19 with only these 2 classic symptoms of the viral infection.CONCLUSIONS:
Severe acute respiratory syndrome coronavirus 2 is known to cause conjunctivitis and has demonstrated transmissibility through ocular secretions. Acute immune and inflammatory dysregulations have been seen in cases of COVID-19 through various mechanisms. COVID-19 infection may potentially compromise ocular immune privilege contributing to acute corneal graft rejection.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Endothelium, Corneal
/
Keratoplasty, Penetrating
/
SARS-CoV-2
/
COVID-19
/
Graft Rejection
/
Keratoconus
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Cornea
Year:
2021
Document Type:
Article
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