The impact of the SARS-CoV-2 pandemic and COVID-19 on lung transplantation in the UK: Lessons learned from the first wave.
Clin Transplant
; 35(3): e14210, 2021 03.
Article
in English
| MEDLINE | ID: covidwho-998855
ABSTRACT
BACKGROUND:
Lung transplantation is particularly susceptible to the impact of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, and evaluation of changes to practice is required to inform future decision-making.METHODS:
A retrospective review of the UK Transplant Registry (UKTR) and national survey of UK lung transplant centers has been performed.RESULTS:
There was geographic variation in the prevalence of COVID-19 infection across the UK. The number of donors fell by 48% during the early pandemic period. Lung utilization fell to 10% (compared with 24% for the same period of 2019). The number of lung transplants performed fell by 77% from 53, March to May 2019, to 12. Seven (58%) of these were performed in a single-center, designated "COVID-light." The number of patients who died on the lung transplant waiting list increased, compared to the same period of 2019 (p = .0118). Twenty-six lung transplant recipients with confirmed COVID-19 infection were reported during the study period.CONCLUSION:
As the pandemic continues, reviewing practice and implementing the lessons learned during this period, including the use of robust donor testing strategies and the provision of "COVID-light" hospitals, are vital in ensuring the safe continuation of our lung transplant program.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Tissue Donors
/
Registries
/
Waiting Lists
/
Lung Transplantation
/
Pandemics
/
Transplant Recipients
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Europa
Language:
English
Journal:
Clin Transplant
Journal subject:
Transplantation
Year:
2021
Document Type:
Article
Affiliation country:
Ctr.14210
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