Spontaneous portomesenteric thrombosis in a non-cirrhotic patient with SARS-CoV-2 infection.
BMJ Case Rep
; 13(12)2020 Dec 22.
Article
in English
| MEDLINE | ID: covidwho-999235
ABSTRACT
Intra-abdominal thromboses are a poorly characterised thrombotic complication of COVID-19 and are illustrated in this case. A 42-year-old man with chronic hepatitis B (undetectable viral load, FibroScan 7.4 kPa) developed fever and cough in March 2020. 14 days later, he developed right upper quadrant pain. After being discharged with reassurance, he re-presented with worsening pain on symptom day 25. Subsequent abdominal ultrasound suggested portal vein thrombosis. CT of the abdomen confirmed portal and mid-superior mesenteric vein thromboses. Concurrent CT of the chest suggested COVID-19 infection. While reverse transcription PCR was negative, subsequent antibody serology was positive. Thrombophilia screen excluded inherited and acquired thrombophilia. Having been commenced on apixaban 5 mg two times per day, he is currently asymptomatic. This is the first case of COVID-19-related portomesenteric thrombosis described in the UK. A recent meta-analysis suggests 9.2% of COVID-19 cases develop abdominal pain. Threshold for performing abdominal imaging must be lower to avoid this reversible complication.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Portal Vein
/
Pyrazoles
/
Pyridones
/
Hepatitis B, Chronic
/
Mesenteric Ischemia
/
SARS-CoV-2
/
COVID-19
/
Mesenteric Veins
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
/
Reviews
Topics:
Long Covid
Limits:
Adult
/
Humans
/
Male
Language:
English
Year:
2020
Document Type:
Article
Affiliation country:
Bcr-2020-238906
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