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The immune system view of the coronavirus SARS-CoV-2.
Celardo, Ivana; Pace, Luigia; Cifaldi, Loredana; Gaudio, Carlo; Barnaba, Vincenzo.
  • Celardo I; Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma, Rome, Italy.
  • Pace L; Armenise-Harvard Immune Regulation Unit, Italian Institute for Genomic Medicine, FPO IRCCS Candiolo, Turin, Italy.
  • Cifaldi L; Academic Department of Pediatrics (DPUO),, Ospedale Pediatrico Bambino Gesù,, IRCCS, Rome,, 00165, Italy.
  • Gaudio C; Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", Via Montpellier 1, Rome, 00133, Italy.
  • Barnaba V; Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma, Rome, Italy.
Biol Direct ; 15(1): 30, 2020 12 29.
Article in English | MEDLINE | ID: covidwho-999756
ABSTRACT
Knowing the "point of view" of the immune system is essential to understand the characteristic of a pandemic, such as that generated by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2, responsible for the Coronavirus Disease (COVID)-19. In this review, we will discuss the general host/pathogen interactions dictating protective immune response or immunopathology, addressing the role of immunity or immunopathology in influencing the clinical infection outcome, and debate the potential immunoprophylactic and immunotherapy strategies required to fight the virus infection.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Immune System Type of study: Prognostic study Topics: Vaccines Limits: Animals / Humans Language: English Journal: Biol Direct Year: 2020 Document Type: Article Affiliation country: S13062-020-00283-2

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Immune System Type of study: Prognostic study Topics: Vaccines Limits: Animals / Humans Language: English Journal: Biol Direct Year: 2020 Document Type: Article Affiliation country: S13062-020-00283-2