Patients with COVID-19 Testing Positive for Nucleic Acids of SARS-CoV-2 in Re-examination After Discharge from Hospital: An Analysis of Three Cases / 3例COVID-19出院后核酸复检阳性患者的检测分析

ABSTRACT

Detection of the nucleic acids (NAs) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the “gold standard” for diagnosis of coronavirus disease 2019 (COVID-19). Antibody detection in serum is an important auxiliary method. We undertook retrospective analyses of the results of NA detection and antibody detection in the diagnosis, treatment and isolation of COVID-19 patients at the beginning of the disease as well as upon discharge from hospital. We offered a preliminary discussion on the correlation between NA detection and antibody detection and the infectious factors of COVID-19. Our study can provide a reference for monitoring SARS -CoV-2 infection in the treatment and rehabilitation of patients with COVID-19.

摘要

新型冠状病毒(SARS-CoV-2)核酸检测是新型冠状病毒肺炎(COVID-19)病例确诊的金标准,血清抗体检测是重要辅助手段。本文对重庆市江津区中心医院3例COVID-19出院后核酸复检阳性患者,回顾性分析在疾病初期确诊、治疗出院、转诊隔离全程诊疗过程中患者临床病例及其核酸和抗体检测结果,结合患者体内新冠病毒核酸确诊到完全转阴时间变化,初步探讨COVID-19临床治愈出院患者核酸和抗体检测与疾病传染性因素的相关性,为新冠肺炎患者治疗康复过程的病毒感染监测提供参考。