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Psychological consequences of COVID-19 pandemic in Italian MS patients: signs of resilience?
EuropePMC; 2020.
Preprint in English | EuropePMC | ID: ppcovidwho-307745
ABSTRACT

Background:

Anxiety, depression and reduction of quality of life (QoL) are common in people with multiple sclerosis (pwMS). Fear of getting sick from COVID-19, government’s lockdown and the imposed social distancing might have an impact on psychological distress and QoL.

Objectives:

The aim of our study was to investigate anxiety, depression and QoL changes in pwMS during SARS-CoV-2 outbreak and lockdown in Italy.

Methods:

67 pwMS with a previous (less than 6 months) neuropsychological evaluation before SARS-CoV-2 outbreak (T0) were re-evaluated at the time of the outbreak and lockdown in Italy (T1). They underwent a clinical and neurological evaluation (at T0) and completed the State-Trait Anxiety Inventory (STAI-Y1), the Beck Depression Inventory second edition (BDI-II), and Multiple Sclerosis Quality of Life-54 (MsQoL-54) at T0 and T1. Bonferroni correction for multiple comparisons was applied.

Results:

BDI-II and STAI-Y1 scores did not change between T0 and T1, whereas the satisfaction on sexual function subscale of MsQoL-54 was significantly higher at T1 ( p<0.001 ).

Conclusions:

This is the first study that evaluated mood and QoL levels before and during the lockdown due to COVID-19 pandemic in pwMS. No worsening of anxiety and depression levels was found. Contrariwise, some improvements were noted on QoL, the most reliable regarding the sexual satisfaction.

Full text: Available Collection: Preprints Database: EuropePMC Type of study: Experimental Studies / Prognostic study Language: English Year: 2020 Document Type: Preprint

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Full text: Available Collection: Preprints Database: EuropePMC Type of study: Experimental Studies / Prognostic study Language: English Year: 2020 Document Type: Preprint