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Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients (preprint)
medrxiv; 2020.
Preprint in English | medRxiv | ID: ppzbmed-10.1101.2020.06.07.20125096
ABSTRACT
SARS-CoV-2 outbreak is a world-wide pandemic. The Spike protein plays central role in cell entry of the virus, and triggers significant immuno-response. Our understanding of the immune-response against S protein is still very limited. Herein, we constructed a peptide microarray and analyzed 55 convalescent sera, three areas with rich linear epitopes were identified. Potent neutralizing antibodies enriched from sera by 3 peptides, which do not belong to RBD were revealed.
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Full text: Available Collection: Preprints Database: medRxiv Main subject: COVID-19 Language: English Year: 2020 Document Type: Preprint

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Full text: Available Collection: Preprints Database: medRxiv Main subject: COVID-19 Language: English Year: 2020 Document Type: Preprint