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Molecular Detection and Clinical Characteristics of Bacterial and Viral Main Etiological Agents Causing Respiratory Tract Infections in Tehran, Iran (preprint)
researchsquare; 2021.
Preprint
in English
| PREPRINT-RESEARCHSQUARE | ID: ppzbmed-10.21203.rs.3.rs-279011.v1
ABSTRACT
Background:
Respiratory tract infections are one of the most important infections among military personals, worldwide. The present study aimed to survey the prevalence of bacterial and viral main etiological agents causing respiratory tract infections among the military personnel in Iran. A cross-sectional study was performed from September 2020 to February 2021. Nasopharyngeal swabs were taken from patients, military personnel with respiratory tract infection symptoms. Detection of COVID-19 was performed with one step qRT-PCR method. TaqMan probe-based real-time PCR assay was used for the detection of influenza A and B viruses. The prevalence of adenovirus and M. pneumoniae were determined using nested PCR. Moreover, B. pertussis and S. pyogenes were identified by conventional PCR assay. The detection of H. influenzae was performed by multiplex PCR method.Results:
Overall, 145 patients were included. Among viral pathogens, COVID-19, influenza A virus, and adenovirus were identified in 85.5%, 4.1%, and 1.4% of patients, respectively. Influenza B virus was not detected among military personnel. The frequency of bacteria etiological agents was as follows S. pyogenes (2%), M. pneumoniae (0.7%), H. influenzae (0%), and B. pertussis (0%). Muscle aches (75.9%), headache (70.3%), lethargy (69%), cough (66.2%), stuffy nose (56.6%), fever (53.8%), and sore throat (53.1%) were amongst the most common clinical symptoms.Conclusions:
Results showed that the military personals are the susceptible group to COVID-19 infection. Therefore, the accurate detection and implementation of control strategies such as vaccination are necessary.
Full text:
Available
Collection:
Preprints
Database:
PREPRINT-RESEARCHSQUARE
Main subject:
Pain
/
Respiratory Tract Infections
/
Lethargy
/
Fever
/
COVID-19
/
Headache
Language:
English
Year:
2021
Document Type:
Preprint
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