Cycle Threshold to Test Positivity in COVID-19 for Return to Work Clearance in Health Care Workers.
J Occup Environ Med
; 62(11): 889-891, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: covidwho-1024147
ABSTRACT
OBJECTIVE:
To ascertain whether reverse transcriptase polymerase chain reaction (RT-PCR) cycle amplifications until detection, the cycle threshold (Ct), could help inform return to work (RTW) strategies for health care workers (HCWs) recovering from COVID-19 infection.METHODS:
Sequential Ct data from COVID-19 nasal pharyngeal (NP) RT-PCR testing in all COVID-19 positive HCWs at a single institution. Analysis of Ct in relation to time until negative testing for RTW clearance.RESULTS:
Data for 12 employees showed that time elapsed until RT-PCR test-based RTW clearance ranged from 7 to 57 days (median, 34.5 days). Lower initial Ct correlated with the total time elapsed until clearance (râ=â-0.80; Pâ=â0.002).CONCLUSION:
Considering the RT-PCR Ct, which correlates with the estimated viral load, may help inform RTW planning and decision making beyond solely relying on dichotomized positive/negative results.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Neumonía Viral
/
Personal de Salud
/
Infecciones por Coronavirus
/
Técnicas de Laboratorio Clínico
/
Reinserción al Trabajo
/
Betacoronavirus
Tipo de estudio:
Estudio de cohorte
/
Estudios diagnósticos
/
Estudio observacional
/
Estudio pronóstico
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
J Occup Environ Med
Asunto de la revista:
Medicina Ocupacional
/
Salud Ambiental
Año:
2020
Tipo del documento:
Artículo
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