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SARS-CoV-2 related pneumonia in an adult with cystic fibrosis: natural favourable clinical course or effective therapy?
Giglia, Maddalena; Beci, Giacomo; Rosselli Del Turco, Elena; Guardigni, Viola; Amedeo, Alberto; Cucchetto, Giulia; Verucchi, Gabriella; Cipolli, Marco; Calza, Leonardo; Viale, Pierluigi.
  • Giglia M; Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna. maddalena.giglia@studio.unibo.it.
  • Beci G; Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna. giacomo.beci@studio.unibo.it.
  • Rosselli Del Turco E; Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna. erossellidelturco@gmail.com.
  • Guardigni V; Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna. viola.guardigni2@unibo.it.
  • Amedeo A; Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna. alberto.amedeo@studio.unibo.it.
  • Cucchetto G; Cystic Fibrosis Regional Centre, AOUI Verona. giulia.cucchetto@aovr.veneto.it.
  • Verucchi G; Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna. gabriella.verucchi@unibo.it.
  • Cipolli M; Cystic Fibrosis Regional Centre, AOUI Verona. marco.cipolli@aovr.veneto.it.
  • Calza L; Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna. leonardo.calza@unibo.it.
  • Viale P; Department of Medical and Surgical Sciences, Clinics of Infectious Diseases, S. Orsola-Malpighi Hospital, "Alma Mater Studiorum" University of Bologna. pierluigi.viale@unibo.it.
Monaldi Arch Chest Dis ; 90(4)2020 Dec 23.
Artículo en Inglés | MEDLINE | ID: covidwho-1042105
ABSTRACT
We report the case of a man affected by cystic fibrosis who developed a severe SARS-CoV-2 related pneumonia in March 2020. In addition to lopinavir/ritonavir and hydroxychloroquine, he was treated with two doses of tocilizumab, displaying a significant clinical improvement. This is the first case described in the literature of an adult patient affected by cystic fibrosis who received tocilizumab for COVID-19, with documented total recovery, also assessed by a spirometry.
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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones del Sistema Respiratorio / Ritonavir / Fibrosis Quística / Lopinavir / Anticuerpos Monoclonales Humanizados / SARS-CoV-2 / COVID-19 / Tratamiento Farmacológico de COVID-19 / Hidroxicloroquina Tipo de estudio: Reporte de caso / Estudios diagnósticos / Estudio experimental / Estudio pronóstico Tópicos: Covid persistente / Vacunas Límite: Adulto / Humanos / Masculino Idioma: Inglés Año: 2020 Tipo del documento: Artículo

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones del Sistema Respiratorio / Ritonavir / Fibrosis Quística / Lopinavir / Anticuerpos Monoclonales Humanizados / SARS-CoV-2 / COVID-19 / Tratamiento Farmacológico de COVID-19 / Hidroxicloroquina Tipo de estudio: Reporte de caso / Estudios diagnósticos / Estudio experimental / Estudio pronóstico Tópicos: Covid persistente / Vacunas Límite: Adulto / Humanos / Masculino Idioma: Inglés Año: 2020 Tipo del documento: Artículo