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Prevalence of COVID-19-related symptoms by age group.
Unim, Brigid; Palmieri, Luigi; Lo Noce, Cinzia; Brusaferro, Silvio; Onder, Graziano.
  • Unim B; Department of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore di Sanità, Via Giano della Bella 34, 00162, Rome, Italy. brigid.unim@iss.it.
  • Palmieri L; Department of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore di Sanità, Via Giano della Bella 34, 00162, Rome, Italy.
  • Lo Noce C; Department of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore di Sanità, Via Giano della Bella 34, 00162, Rome, Italy.
  • Brusaferro S; Office of the President, Istituto Superiore di Sanità, Rome, Italy.
  • Onder G; Department of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore di Sanità, Via Giano della Bella 34, 00162, Rome, Italy.
Aging Clin Exp Res ; 33(4): 1145-1147, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: covidwho-1111389
ABSTRACT

BACKGROUND:

Severe acute respiratory syndrome coronavirus 2 has caused over 95 million confirmed cases of COVID-19 and over 2 million deaths worldwide. According to current literature data, older adults have higher risk of severe disease and mortality due to COVID-19. It is also known that older adults often do not present typical symptoms of diseases. The aim of the study was to assess if the prevalence of typical COVID-19-related symptoms varies by age group.

METHODS:

Medical charts of a random sample of COVID-19 patients dying in-hospital were retrieved through an integrated national surveillance system and reviewed by a group of researchers at the Italian National Institute of Health. Detailed information on COVID-19-related symptoms were extracted and analyzed.

RESULTS:

3241 confirmed cases of COVID-19-related deaths were identified from 4391 reviewed medical charts. The mean number of COVID-19-related symptoms progressively declined with age, from 2.1 in patients aged < 60 years to 1.7 in those aged 90 years or older (p < 0.001). Moreover, fever, cough, and diarrhea significantly declined with increasing age.

CONCLUSIONS:

Older adults have atypical presentation of symptoms and may be paucisymptomatic. This may lead to a diagnostic and therapeutic delay which aggravates the prognosis of COVID-19. Special attention should be posed when assessing individuals aged 65 years and older with suspected COVID-19.
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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Reporte de caso / Estudio observacional / Estudio pronóstico / Ensayo controlado aleatorizado Límite: Anciano / Humanos País/Región como asunto: Europa Idioma: Inglés Revista: Aging Clin Exp Res Asunto de la revista: Geriatria Año: 2021 Tipo del documento: Artículo País de afiliación: S40520-021-01809-y

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Reporte de caso / Estudio observacional / Estudio pronóstico / Ensayo controlado aleatorizado Límite: Anciano / Humanos País/Región como asunto: Europa Idioma: Inglés Revista: Aging Clin Exp Res Asunto de la revista: Geriatria Año: 2021 Tipo del documento: Artículo País de afiliación: S40520-021-01809-y