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Abrupt Late-onset Psychosis as a Presentation of Coronavirus 2019 Disease (COVID-19): A Longitudinal Case Report.
J Psychiatr Pract ; 27(2): 131-136, 2021 Mar 05.
Artículo en Inglés | MEDLINE | ID: covidwho-1291391
ABSTRACT

INTRODUCTION:

Coronavirus Disease 2019 (COVID-19) is a pandemic infection caused by the Severe Acute Respiratory Syndrome 2 Coronavirus (SARS-2-CoV). Although most prominently associated with pulmonary manifestations, COVID-19 is increasingly implicated in neuropsychiatric complications, including delirium and psychosis. There is a potential causal link between COVID-19 infection and psychotic symptoms; however, case reports to date have been incomplete, as the patients described had known psychiatric histories or other plausible medical causes for altered mental status. We present a longitudinal case of COVID-19 psychosis in a patient who underwent comprehensive diagnostic evaluation. This case is a contribution to the inchoate characterization of neuropsychiatric manifestations of COVID-19 infection. CASE REPORT We present a case of late-onset psychosis in a middle-aged man with no psychiatric history who tested positive for COVID-19 on admission following a recently resolved upper respiratory illness. His acute presentation-characterized by delusions, hallucinations, and disorganized thought and behavior, for which he required inpatient medical admission and subsequent inpatient psychiatric hospitalization-was successfully treated. During his hospitalization, he underwent comprehensive medical and neurological workup (including neuroimaging; electroencephalography; and serum and cerebrospinal fluid testing) that was grossly unremarkable.

DISCUSSION:

Despite myriad potential causes of the patient's psychosis, this patient's diagnostic workup was largely unrevealing, apart from his nasopharyngeal SARS-2-CoV reverse transcriptase polymerase chain reaction assay. As such, psychosis secondary to COVID-19 infection emerged as the presumptive diagnosis.
Asunto(s)

Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Trastornos Psicóticos / COVID-19 Tipo de estudio: Reporte de caso / Estudio de cohorte / Estudios diagnósticos / Estudio experimental / Estudio observacional / Estudio pronóstico Tópicos: Covid persistente Límite: Humanos / Masculino / Middle aged Idioma: Inglés Revista: J Psychiatr Pract Asunto de la revista: Psiquiatria Año: 2021 Tipo del documento: Artículo

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Trastornos Psicóticos / COVID-19 Tipo de estudio: Reporte de caso / Estudio de cohorte / Estudios diagnósticos / Estudio experimental / Estudio observacional / Estudio pronóstico Tópicos: Covid persistente Límite: Humanos / Masculino / Middle aged Idioma: Inglés Revista: J Psychiatr Pract Asunto de la revista: Psiquiatria Año: 2021 Tipo del documento: Artículo