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COVID-19 triggering mucormycosis in a susceptible patient: a new phenomenon in the developing world?
Revannavar, Shweta Mallikarjun; P S, Supriya; Samaga, Laxminarayana; V K, Vineeth.
  • Revannavar SM; General Medicine, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India shweta.connect2@gmail.com.
  • P S S; General Medicine, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India.
  • Samaga L; General Medicine, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India.
  • V K V; General Medicine, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India.
BMJ Case Rep ; 14(4)2021 Apr 27.
Artículo en Inglés | MEDLINE | ID: covidwho-1206018
ABSTRACT
A middle-aged woman with diabetes presented with left-sided facial pain, complete ptosis and fever of short duration. On presentation, she had hyperglycaemia without ketosis. There was total ophthalmoplegia of the left eye with a visual acuity of 6/36. She incidentally tested positive for COVID-19. CT paranasal sinus and MRI brain revealed left-sided pansinusitis with acute infarct in the left parieto-occipital region without angioinvasion. An emergency functional endoscopic sinus procedure was done, which confirmed mucormycosis on histopathological examination. After 1 week of conventional amphotericin B and antibiotics, repeat CT brain showed improvement in mucosal thickening and sinusitis. This case is a rare presentation of mucormycosis associated with rapid progression to orbital apex syndrome with brain infarction in a patient with non-ketotic diabetes and COVID-19. Early diagnosis and treatment are essential to prevent further end-organ damage. It is also interesting that there was no angioinvasion and transient periarterial inflammation was attributed to brain infarction.
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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Enfermedades Orbitales / Enfermedades de los Senos Paranasales / Blefaroptosis / Oftalmoplejía / Complicaciones de la Diabetes / COVID-19 / Mucormicosis Tipo de estudio: Reporte de caso / Estudios diagnósticos / Estudio pronóstico Tópicos: Covid persistente Límite: Femenino / Humanos / Middle aged Idioma: Inglés Año: 2021 Tipo del documento: Artículo País de afiliación: Bcr-2021-241663

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Enfermedades Orbitales / Enfermedades de los Senos Paranasales / Blefaroptosis / Oftalmoplejía / Complicaciones de la Diabetes / COVID-19 / Mucormicosis Tipo de estudio: Reporte de caso / Estudios diagnósticos / Estudio pronóstico Tópicos: Covid persistente Límite: Femenino / Humanos / Middle aged Idioma: Inglés Año: 2021 Tipo del documento: Artículo País de afiliación: Bcr-2021-241663