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A simple cognitive task intervention to prevent intrusive memories after trauma in patients in the Emergency Department: A randomized controlled trial terminated due to COVID-19.
Kanstrup, Marie; Singh, Laura; Göransson, Katarina E; Gamble, Beau; Taylor, Rod S; Iyadurai, Lalitha; Moulds, Michelle L; Holmes, Emily A.
  • Kanstrup M; Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden. marie.kanstrup@ki.se.
  • Singh L; Functional Area Medical Psychology, Karolinska University Hospital, Stockholm, Sweden. marie.kanstrup@ki.se.
  • Göransson KE; Department of Psychology, Uppsala University, Box 1225, 751 42, Uppsala, Sweden. laura.singh@psyk.uu.se.
  • Gamble B; Swedish Collegium for Advanced Study, Uppsala, Sweden. laura.singh@psyk.uu.se.
  • Taylor RS; Emergency and Reparative Medicine Theme, Karolinska University Hospital, Stockholm, Sweden.
  • Iyadurai L; Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
  • Moulds ML; Department of Psychology, Uppsala University, Box 1225, 751 42, Uppsala, Sweden.
  • Holmes EA; MRC/CSO Social and Public Health Sciences Unit & Robertson Centre for Biostatistics, Institute of Health and Well Being, University of Glasgow, Glasgow, UK.
BMC Res Notes ; 14(1): 176, 2021 May 10.
Artículo en Inglés | MEDLINE | ID: covidwho-1223779
ABSTRACT

OBJECTIVE:

This randomised controlled trial (RCT) aimed to investigate the effects of a simple cognitive task intervention on intrusive memories ("flashbacks") and associated symptoms following a traumatic event. Patients presenting to a Swedish emergency department (ED) soon after a traumatic event were randomly allocated (11) to the simple cognitive task intervention (memory cue + mental rotation instructions + computer game "Tetris" for at least 20 min) or control (podcast, similar time). We planned follow-ups at one-week, 1-month, and where possible, 3- and 6-months post-trauma. Anticipated enrolment was N = 148.

RESULTS:

The RCT was terminated prematurely after recruiting N = 16 participants. The COVID-19 pandemic prevented recruitment/testing in the ED because (i) the study required face-to-face contact between participants, psychology researchers, ED staff, and patients, incurring risk of virus transmission; (ii) the host ED site received COVID-19 patients; and (iii) reduced flow of patients otherwise presenting to the ED in non-pandemic conditions (e.g. after trauma). We report on delivery of study procedures, recruitment, treatment adherence, outcome completion (primary

outcome:

number of intrusive memories during week 5), attrition, and limitations. The information presented and limitations may enable our group and others to learn from this terminated study. Trial registration ClinicalTrials.gov NCT04185155 (04-12-2019).
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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Trastornos por Estrés Postraumático / COVID-19 Tipo de estudio: Estudio experimental / Estudio pronóstico / Ensayo controlado aleatorizado Tópicos: Covid persistente Límite: Humanos Idioma: Inglés Revista: BMC Res Notes Año: 2021 Tipo del documento: Artículo País de afiliación: S13104-021-05572-1

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Trastornos por Estrés Postraumático / COVID-19 Tipo de estudio: Estudio experimental / Estudio pronóstico / Ensayo controlado aleatorizado Tópicos: Covid persistente Límite: Humanos Idioma: Inglés Revista: BMC Res Notes Año: 2021 Tipo del documento: Artículo País de afiliación: S13104-021-05572-1