Thromboinflammation: Dynamik physiologischer und pathologischer

ABSTRACT

The orchestral interaction between endothelial dysfunction, activated thrombocytes and other immune cells as well as the concomitant activation of complement lead to simultaneous activation of the immune system and coagulation. An uncontrolled persistence of these physiological mechanisms can induce pathological processes of thromboinflammation. This review article aims to summarise mechanisms leading to thromboinflammation as a cause of venous thromboembolism.