Post-COVID-19 vaccination Guillain-Barre syndrome with sensory ataxia, gaze-evoked nystagmus, mental-status change and positive pathological reflex
Clinical and Experimental Neuroimmunology
; 2023.
Artículo
en Inglés
| EMBASE | ID: covidwho-2318954
ABSTRACT
Background:
Various neurological disorders have been reported after vaccination against coronavirus disease 2019, one of which is Guillain-Barre Syndrome (GBS). Case Presentation We report a case of a 73-year-old woman who developed GBS and extra-GBS manifestations 19 days after the second dose of BNT162b2 mRNA vaccine. She presented lower limb predominant muscle weakness and loss of tendon reflexes. Nerve conduction study showed acute motor and sensory axonal neuropathy. In addition, she developed notable deep sensory ataxia, and showed positive pathological reflex, gaze-evoked nystagmus and altered consciousness, which suggested brainstem involvement. Conclusion(s) This is the first coronavirus disease 2019 vaccine-related GBS complicated with such central nervous system manifestations.Copyright © 2023 Japanese Society for Neuroimmunology.
acute motor and sensory axonal neuropathy; brainstem involvement; COVID-19 vaccine-related Guillain-Barre syndrome; deep sensory ataxia; acute motor axonal neuropathy; aged; article; ataxia; brain stem; case report; central nervous system; clinical article; consciousness; coronavirus disease 2019; electroneurography; female; gaze; human; lower limb; mental health; muscle weakness; optokinetic nystagmus; pathological reflex; peripheral neuropathy; tendon reflex; vaccination; RNA vaccine; tozinameran
Texto completo:
Disponible
Colección:
Bases de datos de organismos internacionales
Base de datos:
EMBASE
Tópicos:
Covid persistente
/
Vacunas
Idioma:
Inglés
Revista:
Clinical and Experimental Neuroimmunology
Año:
2023
Tipo del documento:
Artículo
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