COVID-19 in posttransplant patients-report of 2 cases.
Am J Transplant
; 20(7): 1879-1881, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: covidwho-101378
ABSTRACT
Coronavirus Disease 2019 (COVID-19) has become a pandemic since March 2020. We describe here 2 cases of COVID-19 infection in a posttransplant setting. First one is a 59-year-old renal transplant recipient; the second is a 51-year-old allogeneic bone marrow transplant recipient. Both patients were on immunosuppressant therapy and had stable graft function before COVID-19 infection. After the diagnosis of COVID-19, immunosuppressive agents were discontinued and methylprednisolone with prophylactic antibiotics were initiated, however, the lung injury progressed. The T cells were extremely low in both patients after infection. Both patients died despite the maximal mechanical ventilatory support. Therefore, the prognosis of COVID-19 pneumonia following transplantation is not optimistic and remains guarded. Lower T cell count may be a surrogate for poor outcome.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Neumonía Viral
/
Leucemia Mieloide Aguda
/
Trasplante de Médula Ósea
/
Trasplante de Riñón
/
Infecciones por Coronavirus
/
Receptores de Trasplantes
/
Fallo Renal Crónico
Tipo de estudio:
Reporte de caso
/
Estudios diagnósticos
/
Estudio experimental
/
Estudio pronóstico
/
Ensayo controlado aleatorizado
Tópicos:
Covid persistente
Límite:
Humanos
/
Masculino
/
Middle aged
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Am J Transplant
Asunto de la revista:
Trasplante
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Ajt.15896
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