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COVID-19 in posttransplant patients-report of 2 cases.
Huang, Jiaofeng; Lin, Heng; Wu, Yinlian; Fang, Yingying; Kumar, Rahul; Chen, Gongping; Lin, Su.
  • Huang J; Department of Liver Research Center, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Lin H; Department of Oncology, Fuzhou Pulmonary Hospital, Fuzhou, China.
  • Wu Y; Department of Liver Research Center, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Fang Y; Department of Tuberculosis, the Third People's Hospital of Yichang City, Yichang, China.
  • Kumar R; Department of Gastroenterology and Hepatology, Changi General Hospital, Singapore, Singapore.
  • Chen G; Department of Respiratory, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Lin S; Department of Liver Research Center, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Am J Transplant ; 20(7): 1879-1881, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: covidwho-101378
ABSTRACT
Coronavirus Disease 2019 (COVID-19) has become a pandemic since March 2020. We describe here 2 cases of COVID-19 infection in a posttransplant setting. First one is a 59-year-old renal transplant recipient; the second is a 51-year-old allogeneic bone marrow transplant recipient. Both patients were on immunosuppressant therapy and had stable graft function before COVID-19 infection. After the diagnosis of COVID-19, immunosuppressive agents were discontinued and methylprednisolone with prophylactic antibiotics were initiated, however, the lung injury progressed. The T cells were extremely low in both patients after infection. Both patients died despite the maximal mechanical ventilatory support. Therefore, the prognosis of COVID-19 pneumonia following transplantation is not optimistic and remains guarded. Lower T cell count may be a surrogate for poor outcome.
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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Leucemia Mieloide Aguda / Trasplante de Médula Ósea / Trasplante de Riñón / Infecciones por Coronavirus / Receptores de Trasplantes / Fallo Renal Crónico Tipo de estudio: Reporte de caso / Estudios diagnósticos / Estudio experimental / Estudio pronóstico / Ensayo controlado aleatorizado Tópicos: Covid persistente Límite: Humanos / Masculino / Middle aged País/Región como asunto: Asia Idioma: Inglés Revista: Am J Transplant Asunto de la revista: Trasplante Año: 2020 Tipo del documento: Artículo País de afiliación: Ajt.15896

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Leucemia Mieloide Aguda / Trasplante de Médula Ósea / Trasplante de Riñón / Infecciones por Coronavirus / Receptores de Trasplantes / Fallo Renal Crónico Tipo de estudio: Reporte de caso / Estudios diagnósticos / Estudio experimental / Estudio pronóstico / Ensayo controlado aleatorizado Tópicos: Covid persistente Límite: Humanos / Masculino / Middle aged País/Región como asunto: Asia Idioma: Inglés Revista: Am J Transplant Asunto de la revista: Trasplante Año: 2020 Tipo del documento: Artículo País de afiliación: Ajt.15896