The Role of Genetic Sex and Mitochondria in Response to COVID-19 Infection.
Int Arch Allergy Immunol
; 181(8): 629-634, 2020.
Artículo
en Inglés
| MEDLINE | ID: covidwho-610697
ABSTRACT
The difference between the female and male immune response to COVID-19 infection, and infections in general, is multifactorial. The well-known determiners of the immune response, such as X and Y chromosomes, sex hormones, and microbiota, are functionally interconnected and influence each other in shaping the organism's immunity. We focus our commentary on the interplay between the genetic sex and mitochondria and how this may affect a sex-dependent immune response in COVID-19 infection. Realizing the existence of these interactions may help in designing novel methods or fine-tuning the existing and routine therapies to fight COVID-19 and other infections.
Palabras clave
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Neumonía Viral
/
Cromosomas Sexuales
/
Infecciones por Coronavirus
/
Betacoronavirus
/
Mitocondrias
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Int Arch Allergy Immunol
Asunto de la revista:
Alergia e Inmunología
Año:
2020
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS