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The Novel Coronavirus Disease (COVID-19): A PRISMA Systematic Review and Meta-Analysis of Clinical and Paraclinical Characteristics.
Hasani, Hamidreza; Mardi, Shayan; Shakerian, Sareh; Taherzadeh-Ghahfarokhi, Nooshin; Mardi, Parham.
  • Hasani H; Eye Research Center, The Five Senses Institute, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
  • Mardi S; Department of Ophthalmology, Madani Hospital, Alborz University of Medical Sciences, Karaj, Iran.
  • Shakerian S; Student Research Committee, Alborz University of Medical Sciences, Karaj, Iran.
  • Taherzadeh-Ghahfarokhi N; Departments of Community Based Education of Health Sciences, Virtual School of Medical Education and Management, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Mardi P; Student Research Committee, Alborz University of Medical Sciences, Karaj, Iran.
Biomed Res Int ; 2020: 3149020, 2020.
Artículo en Inglés | MEDLINE | ID: covidwho-733121
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ABSTRACT
An outbreak of pneumonia, caused by a novel coronavirus (SARS-CoV-2), was identified in China in December 2019. This virus expanded worldwide, causing global concern. Although clinical, laboratory, and imaging features of COVID-19 are characterized in some observational studies, we undertook a systematic review and meta-analysis to assess the frequency of these features. We did a systematic review and meta-analysis using three databases to identify clinical, laboratory, and computerized tomography (CT) scanning features of rRT-PCR confirmed cases of COVID-19. Data for 3420 patients from 30 observational studies were included. Overall, the results showed that fever (84.2%, 95% CI 82.6-85.7), cough (62%, 95% CI 60-64), and fatigue (39.4%, 95% CI 37.2-41.6%) are the most prevalent symptoms in COVID-19 patients. Increased CRP level, decreased lymphocyte count, and increased D-dimer level were the most common laboratory findings. Among COVID-19 patients, 92% had a positive CT finding, most prevalently ground-glass opacification (GGO) (60%, 95% CI 58-62) and peripheral distribution opacification (64%, 95% CI 60-69). These results demonstrate the clinical, paraclinical, and imaging features of COVID-19.
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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones por Coronavirus / Pandemias Tipo de estudio: Estudios diagnósticos / Estudio observacional / Estudio pronóstico / Revisiones / Revisión sistemática/Meta análisis Tópicos: Covid persistente Límite: Adolescente / Adulto / Anciano / Niño / Child, preschool / Femenino / Humanos / Lactante / Masculino / Middle aged Idioma: Inglés Revista: Biomed Res Int Año: 2020 Tipo del documento: Artículo País de afiliación: 2020

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones por Coronavirus / Pandemias Tipo de estudio: Estudios diagnósticos / Estudio observacional / Estudio pronóstico / Revisiones / Revisión sistemática/Meta análisis Tópicos: Covid persistente Límite: Adolescente / Adulto / Anciano / Niño / Child, preschool / Femenino / Humanos / Lactante / Masculino / Middle aged Idioma: Inglés Revista: Biomed Res Int Año: 2020 Tipo del documento: Artículo País de afiliación: 2020