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Coronavirus disease 2019-associated rapidly progressive organizing pneumonia with fibrotic feature: Two case reports.
Okamori, Satoshi; Lee, Ho; Kondo, Yasushi; Akiyama, Yuto; Kabata, Hiroki; Kaneko, Yuko; Ishii, Makoto; Hasegawa, Naoki; Fukunaga, Koichi.
  • Okamori S; Division of Pulmonary Medicine.
  • Lee H; Division of Pulmonary Medicine.
  • Kondo Y; Division of Rheumatology, Department of Medicine.
  • Akiyama Y; Division of Pulmonary Medicine.
  • Kabata H; Division of Pulmonary Medicine.
  • Kaneko Y; Division of Rheumatology, Department of Medicine.
  • Ishii M; Division of Pulmonary Medicine.
  • Hasegawa N; Center for Infection Diseases and Infection Control, Keio University School of Medicine, Shinjuku, Tokyo, Japan.
  • Fukunaga K; Division of Pulmonary Medicine.
Medicine (Baltimore) ; 99(35): e21804, 2020 Aug 28.
Artículo en Inglés | MEDLINE | ID: covidwho-740204
ABSTRACT

INTRODUCTION:

Pneumonia is one of the most important characteristics of coronavirus disease 2019 (COVID-19) and imaging findings of COVID-19 pneumonia are diverse and change over disease course. However, the detailed clinical course of organizing pneumonia (OP) caused by COVID-19 has not been clarified. PATIENT CONCERNS A 60-year-old man and a 61-year-old woman diagnosed with mild COVID-19 were admitted to our hospital. Their respiratory symptoms were deteriorating even after initiating treatment with antiviral drugs. DIAGNOSIS Chest X-rays and computed tomography scan showed a rapid progression of linear consolidation with reversed halo sign, distributed in subpleural and peri-bronchial regions. They also presented with pulmonary fibrosis findings, including traction bronchiectasis and marked lung volume reduction. They were diagnosed with rapidly progressing OP.

INTERVENTIONS:

They were treated with systemic corticosteroids.

OUTCOMES:

The patients' imaging findings and respiratory conditions improved rapidly without any adverse effects.

CONCLUSION:

Physicians should carefully monitor patients with COVID-19, as they can develop rapidly progressive and fibrotic OP, which respond to corticosteroids.
Asunto(s)

Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Fibrosis Pulmonar / Prednisolona / Infecciones por Coronavirus / Pandemias / Pulmón Tipo de estudio: Reporte de caso / Estudios diagnósticos / Estudio pronóstico Tópicos: Covid persistente Límite: Femenino / Humanos / Masculino / Middle aged Idioma: Inglés Revista: Medicine (Baltimore) Año: 2020 Tipo del documento: Artículo

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Fibrosis Pulmonar / Prednisolona / Infecciones por Coronavirus / Pandemias / Pulmón Tipo de estudio: Reporte de caso / Estudios diagnósticos / Estudio pronóstico Tópicos: Covid persistente Límite: Femenino / Humanos / Masculino / Middle aged Idioma: Inglés Revista: Medicine (Baltimore) Año: 2020 Tipo del documento: Artículo