The role of serological testing in the SARS-CoV-2 outbreak.
S Afr Med J
; 110(9): 842-845, 2020 07 17.
Artículo
en Inglés
| MEDLINE | ID: covidwho-743542
ABSTRACT
Antibody tests for the novel coronavirus, SARS-CoV2, have been developed both as rapid diagnostic assays and for high-throughput formal serology platforms. Although these tests may be a useful adjunct to a diagnostic strategy, they have a number of limitations. Because of the antibody and viral dynamics of the coronavirus, their sensitivity can be variable, especially at early time points after symptom onset. Additional data are required on the performance of the tests in the South African population, especially with regard to development and persistence of antibody responses and whether antibodies are protective against reinfection. These tests may, however, be useful in guiding the public health response, providing data for research (including seroprevalence surveys and vaccine initiatives) and development of therapeutic strategies.
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Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Neumonía Viral
/
Pruebas Inmunológicas
/
Pruebas Serológicas
/
Infecciones por Coronavirus
/
Técnicas de Laboratorio Clínico
/
Pandemias
/
Betacoronavirus
Tipo de estudio:
Estudios diagnósticos
/
Estudio observacional
/
Estudio pronóstico
Tópicos:
Covid persistente
/
Vacunas
Límite:
Humanos
País/Región como asunto:
Africa
Idioma:
Inglés
Revista:
S Afr Med J
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Sudáfrica
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