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COVID-19 in a Severely Immunosuppressed Patient With Life-Threatening Eosinophilic Granulomatosis With Polyangiitis.
Schramm, Markus A; Venhoff, Nils; Wagner, Dirk; Thiel, Jens; Huzly, Daniela; Craig-Mueller, Nils; Panning, Marcus; Hengel, Hartmut; Kern, Winfried V; Voll, Reinhard E.
  • Schramm MA; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Venhoff N; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Wagner D; Division of Infectious Diseases, Department of Internal Medicine II, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Thiel J; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Huzly D; Institute of Virology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Craig-Mueller N; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Panning M; Institute of Virology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Hengel H; Institute of Virology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Kern WV; Division of Infectious Diseases, Department of Internal Medicine II, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Voll RE; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Front Immunol ; 11: 2086, 2020.
Artículo en Inglés | MEDLINE | ID: covidwho-771524
ABSTRACT
Immunosuppressive therapies increase the susceptibility of patients to infections. The current pandemic with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compels clinicians to develop recommendations for successful clinical management and surveillance of immunocompromised patients at high risk for severe disease progression. With only few case studies published on SARS-CoV-2 infection in patients with rheumatic diseases, we report a 25-year-old male who developed moderate coronavirus disease 2019 (COVID-19) with fever, mild dyspnea, and no major complications despite having received high-dose prednisolone, cyclophosphamide, and rituximab for the treatment of highly active, life-threatening eosinophilic granulomatosis with polyangiitis (EGPA).
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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Síndrome de Churg-Strauss / Granulomatosis con Poliangitis / Infecciones por Coronavirus / Ciclofosfamida / Betacoronavirus / Inmunosupresores Tipo de estudio: Reporte de caso / Estudio pronóstico Tópicos: Covid persistente Límite: Adulto / Humanos / Masculino Idioma: Inglés Revista: Front Immunol Año: 2020 Tipo del documento: Artículo País de afiliación: Fimmu.2020.02086

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Síndrome de Churg-Strauss / Granulomatosis con Poliangitis / Infecciones por Coronavirus / Ciclofosfamida / Betacoronavirus / Inmunosupresores Tipo de estudio: Reporte de caso / Estudio pronóstico Tópicos: Covid persistente Límite: Adulto / Humanos / Masculino Idioma: Inglés Revista: Front Immunol Año: 2020 Tipo del documento: Artículo País de afiliación: Fimmu.2020.02086