Diagnosing COVID-19: The Disease and Tools for Detection.

Udugama, Buddhisha; Kadhiresan, Pranav; Kozlowski, Hannah N; Malekjahani, Ayden; Osborne, Matthew; Li, Vanessa Y C; Chen, Hongmin; Mubareka, Samira; Gubbay, Jonathan B; Chan, Warren C W

Udugama, Buddhisha; Kadhiresan, Pranav; Kozlowski, Hannah N; Malekjahani, Ayden; Osborne, Matthew; Li, Vanessa Y C; Chen, Hongmin; Mubareka, Samira; Gubbay, Jonathan B; Chan, Warren C W.

Udugama B; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada.
Kadhiresan P; Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada.
Kozlowski HN; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada.
Malekjahani A; Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada.
Osborne M; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada.
Li VYC; Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada.
Chen H; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada.
Mubareka S; Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada.
Gubbay JB; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada.
Chan WCW; Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada.

ACS Nano ; 14(4): 3822-3835, 2020 04 28.

Artículo en Inglés | MEDLINE | ID: covidwho-832348

ABSTRACT

ABSTRACT

COVID-19 has spread globally since its discovery in Hubei province, China in December 2019. A combination of computed tomography imaging, whole genome sequencing, and electron microscopy were initially used to screen and identify SARS-CoV-2, the viral etiology of COVID-19. The aim of this review article is to inform the audience of diagnostic and surveillance technologies for SARS-CoV-2 and their performance characteristics. We describe point-of-care diagnostics that are on the horizon and encourage academics to advance their technologies beyond conception. Developing plug-and-play diagnostics to manage the SARS-CoV-2 outbreak would be useful in preventing future epidemics.

Asunto(s)

Betacoronavirus/patogenicidad; Técnicas de Laboratorio Clínico; Infecciones por Coronavirus/diagnóstico; Neumonía Viral/diagnóstico; Pruebas en el Punto de Atención; Teléfono Inteligente; COVID-19; Prueba de COVID-19; Humanos; Aplicaciones Móviles; Técnicas de Amplificación de Ácido Nucleico; Pandemias; Vigilancia de la Población; Reacción en Cadena en Tiempo Real de la Polimerasa; SARS-CoV-2; Tomografía Computarizada por Rayos X; Proteínas Virales/análisis

Palabras clave

COVID-19; PCR; SARS-CoV-2; diagnostics; pandemic; surveillance

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Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones por Coronavirus / Técnicas de Laboratorio Clínico / Teléfono Inteligente / Pruebas en el Punto de Atención / Betacoronavirus Tipo de estudio: Estudios diagnósticos / Estudio de etiologia / Estudio pronóstico Límite: Humanos Idioma: Inglés Revista: ACS Nano Año: 2020 Tipo del documento: Artículo País de afiliación: Acsnano.0c02624

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