Your browser doesn't support javascript.
Chest CT features and progression of patients with coronavirus disease 2019.
Xie, Linjun; Hou, Keke; Xu, Huayan; Fu, Hang; Xu, Rong; Liu, Hui; Zhou, Zhongqin; Li, Zhenlin; Yang, Ming; Guo, Yingkun.
  • Xie L; Department of Radiology; Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education; West China Second University Hospital, Sichuan University;20# South Renmin Road, Chengdu, Sichuan 610041, China.
  • Hou K; Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu, China.
  • Xu H; Department of Radiology; Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education; West China Second University Hospital, Sichuan University;20# South Renmin Road, Chengdu, Sichuan 610041, China.
  • Fu H; Department of Radiology; Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education; West China Second University Hospital, Sichuan University;20# South Renmin Road, Chengdu, Sichuan 610041, China.
  • Xu R; Department of Radiology; Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education; West China Second University Hospital, Sichuan University;20# South Renmin Road, Chengdu, Sichuan 610041, China.
  • Liu H; Department of Radiology; Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education; West China Second University Hospital, Sichuan University;20# South Renmin Road, Chengdu, Sichuan 610041, China.
  • Zhou Z; Department of Radiology; Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education; West China Second University Hospital, Sichuan University;20# South Renmin Road, Chengdu, Sichuan 610041, China.
  • Li Z; Department of Radiology, West China Hospital, Sichuan University, 37# GuoXue Xiang, Chengdu, Sichuan 610041, China.
  • Yang M; Department of Respiratory Medicine, Public Health Clinical Center of Chengdu, Chengdu, China.
  • Guo Y; Department of Radiology; Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education; West China Second University Hospital, Sichuan University;20# South Renmin Road, Chengdu, Sichuan 610041, China.
Br J Radiol ; 93(1116): 20200219, 2020 Dec 01.
Artículo en Inglés | MEDLINE | ID: covidwho-927047
ABSTRACT

OBJECTIVES:

Coronavirus disease 2019 (COVID-19) is a major public health emergency. It poses a grave threat to human life and health. The purpose of the study is to investigate the chest CT findings and progression of the disease observed in COVID-19 patients.

METHODS:

Forty-nine confirmed cases of adult COVID-19 patients with common type, severe and critically severe type were included in this retrospective single-center study. The thin-section chest CT features and progress of the disease were evaluated. The clinical and chest imaging findings of COVID-19 patients with different severity types were compared. The CT severity score and MuLBSTA score (a prediction of mortality risk) were calculated in those patients.

RESULTS:

Among the 49 patients, 35 patients (71%) were common type and 14 patients (28%) were severe and critically severe type. Nearly all patients (98%) had pure ground-glass opacities (GGO) in CT imaging. Of the severe and critically severe type patients, 86% exhibited GGO with consolidation, in comparison with 54% of the patients with common type. Fibrosis presented in 79% of the severe and critically severe type patients and 43% of the common type patients. The severe and critically severe type patients were significantly more prone to experience five-lobe involvement compared to the common type patients (p = 0.002). The severe and critically severe type patients also had higher CT severity and MuLBSTA scores than the common type patients (5.43 ± 2.38 vs 3.37 ± 2.40, p < 0.001;and 10.21 ± 3.83 vs 4.63 ± 3.43, p < 0.001, respectively). MuLBSTA score was positively correlated with admittance to the intensive care unit (p = 0.005, r = 0.351). Nineteen patients underwent three times CT scan. The interval between first and second CT scan was 4[4,8] days, second and third was 3[2,4] days. There were greater improvements in the third CT follow-up findings compared to the second (p = 0.002).

CONCLUSIONS:

The severe and critically severe type patients often experienced more severe lung lesions, including GGO with consolidation. The CT severity score and MuLBSTA score may be helpful for the assessment of COVID-19 severity and progression. ADVANCES IN KNOWLEDGE Chest CT has the value of evaluated radiographical features of COVID-19 and allow for dynamic observation of the disease progression. Considering coagulation disorder of COVID-19, MuLBSTA score may need to be updated to increase new understanding of COVID-19.
Asunto(s)

Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Tomografía Computarizada por Rayos X / Infecciones por Coronavirus / Pulmón Tipo de estudio: Estudio de cohorte / Estudios diagnósticos / Estudio experimental / Estudio observacional / Estudio pronóstico Límite: Adulto / Anciano / Femenino / Humanos / Masculino / Middle aged / Young_adult Idioma: Inglés Revista: Br J Radiol Año: 2020 Tipo del documento: Artículo País de afiliación: Bjr.20200219

Similares

MEDLINE

...
LILACS

LIS


Texto completo: Disponible Colección: Bases de datos internacionales Base de datos: MEDLINE Asunto principal: Neumonía Viral / Tomografía Computarizada por Rayos X / Infecciones por Coronavirus / Pulmón Tipo de estudio: Estudio de cohorte / Estudios diagnósticos / Estudio experimental / Estudio observacional / Estudio pronóstico Límite: Adulto / Anciano / Femenino / Humanos / Masculino / Middle aged / Young_adult Idioma: Inglés Revista: Br J Radiol Año: 2020 Tipo del documento: Artículo País de afiliación: Bjr.20200219