Does High Cardiorespiratory Fitness Confer Some Protection Against Proinflammatory Responses After Infection by SARS-CoV-2?
Obesity (Silver Spring)
; 28(8): 1378-1381, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: covidwho-980210
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated in China in late 2019 and has since spread rapidly to every continent in the world. This pandemic continues to cause widespread personal suffering, along with severe pressure on medical and health care providers. The symptoms of SARS-CoV-2 and the subsequent prognosis are worsened in individuals who have preexisting comorbidities prior to infection by the virus. Individuals with obesity or overweight, insulin resistance, and diabetes typically have chronic low-grade inflammation characterized by increased levels of several proinflammatory cytokines and the inflammasome; this state predisposes to greater risk for infection along with more adverse outcomes. Here, we consider whether a high level of cardiorespiratory fitness induced by prior exercise training may confer some innate immune protection against COVID-19 by attenuating the "cytokine storm syndrome" often experienced by "at risk" individuals.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
MEDLINE
Asunto principal:
Neumonía Viral
/
Estado de Salud
/
Citocinas
/
Infecciones por Coronavirus
/
Capacidad Cardiovascular
Tipo de estudio:
Estudio pronóstico
Tópicos:
Covid persistente
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Obesity (Silver Spring)
Asunto de la revista:
Ciencias Nutricionales
/
Fisiología
/
Metabolismo
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Oby.22849
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