Comparison of Blood Counts and Markers of Inflammation and Coagulation in Patients With and Without COVID-19 Presenting to the Emergency Department in Seattle, WA.
Am J Clin Pathol
; 156(2): 185-197, 2021 07 06.
Article
Dans Anglais
| MEDLINE | ID: covidwho-1276141
ABSTRACT
OBJECTIVES:
We compared complete blood count (CBC) with differential and markers of inflammation and coagulation in patients with and without coronavirus disease 2019 (COVID-19) presenting to emergency departments in Seattle, WA.METHODS:
We reviewed laboratory values for 1 week following each COVID-19 test for adult patients who received a standard severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription polymerase chain reaction (RT-PCR) test before April 13, 2020. Results were compared by COVID-19 status and clinical course.RESULTS:
In total 1,027 patients met inclusion criteria. Patients with COVID-19 (n = 155) had lower leukocytes (P < .0001), lymphocytes (P < .0001), platelets (P < .0001), and higher hemoglobin (P = .0140) than those without, but absolute differences were small. Serum albumin was lower in patients with COVID-19 (P < .0001) and serum albumin, neutrophil to lymphocyte ratio (NLR), and red cell distribution width (RDW) were each associated with disease severity. NLR did not differ between patients with COVID-19 and those without (P = .8012).CONCLUSIONS:
Patients with COVID-19 had modestly lower leukocyte, lymphocyte, and platelet counts and higher hemoglobin values than patients without COVID-19. The NLR, serum albumin, and RDW varied with disease severity, regardless of COVID-19 status.Mots clés
Texte intégral:
Disponible
Collection:
Bases de données internationales
Base de données:
MEDLINE
Sujet Principal:
Hémogramme
/
Coagulation sanguine
/
Lymphocytes
/
COVID-19
/
Inflammation
Type d'étude:
Étude diagnostique
/
Étude pronostique
Limites du sujet:
Adulte
/
Humains
/
Mâle
/
Adulte d'âge moyen
langue:
Anglais
Revue:
Am J Clin Pathol
Année:
2021
Type de document:
Article
Pays d'affiliation:
Ajcp
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