Differences in the case fatality risks associated with SARS-CoV-2 Delta and non-Delta variants in relation to vaccine coverage: An early ecological study in the United Kingdom.

Zhao, Shi; Lou, Jingzhi; Cao, Lirong; Chong, Ka Chun; Zee, Benny C Y; Chan, Paul K S; Wang, Maggie H

Zhao, Shi; Lou, Jingzhi; Cao, Lirong; Chong, Ka Chun; Zee, Benny C Y; Chan, Paul K S; Wang, Maggie H.

Zhao S; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; CUHK Shenzhen Research Institute, Shenzhen, China.
Lou J; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China.
Cao L; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; CUHK Shenzhen Research Institute, Shenzhen, China. Electronic address: caolr@link.cuhk.edu.hk.
Chong KC; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; CUHK Shenzhen Research Institute, Shenzhen, China. Electronic address: marc@cuhk.edu.hk.
Zee BCY; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; CUHK Shenzhen Research Institute, Shenzhen, China. Electronic address: bzee@cuhk.edu.hk.
Chan PKS; Department of Microbiology, Chinese University of Hong Kong, Hong Kong, China. Electronic address: paulkschan@cuhk.edu.hk.
Wang MH; JC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; CUHK Shenzhen Research Institute, Shenzhen, China. Electronic address: maggiew@cuhk.edu.hk.

Infect Genet Evol ; 97: 105162, 2022 01.

Article Dans Anglais | MEDLINE | ID: covidwho-1540856

ABSTRACT

ABSTRACT

The circulation of SARS-CoV-2 Delta (i.e., B.1.617.2) variants challenges the pandemic control. Our analysis showed that in the United Kingdom (UK), the reported case fatality ratio (CFR) decreased from May to July 2021 for non-Delta variant, whereas the decreasing trends of the CFR of Delta variant appeared weak and insignificant. The association between vaccine coverage and CFR might be stratified by different circulating variants. Due to the limitation of ecological study design, the interpretation of our results should be treated with caution.

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COVID-19; Case fatality risk; Delta variants; United Kingdom; Vaccine

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Texte intégral: Disponible Collection: Bases de données internationales Base de données: MEDLINE Sujet Principal: Couverture vaccinale / Vaccins contre la COVID-19 / SARS-CoV-2 / COVID-19 Type d'étude: Étude observationnelle / Étude pronostique Les sujets: Vaccins / Variantes Limites du sujet: Humains Pays comme sujet: Europe langue: Anglais Revue: Infect Genet Evol Thème du journal: Biologie / Maladies transmissibles / Génétique Année: 2022 Type de document: Article Pays d'affiliation: J.meegid.2021.105162

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