Epidemiology and Genetic Analysis of SARS-CoV-2 in Myanmar during the Community Outbreaks in 2020.
Viruses
; 14(2)2022 01 27.
Article
Dans Anglais
| MEDLINE | ID: covidwho-1662708
ABSTRACT
We aimed to analyze the situation of the first two epidemic waves in Myanmar using the publicly available daily situation of COVID-19 and whole-genome sequencing data of SARS-CoV-2. From March 23 to December 31, 2020, there were 33,917 confirmed cases and 741 deaths in Myanmar (case fatality rate of 2.18%). The first wave in Myanmar from March to July was linked to overseas travel, and then a second wave started from Rakhine State, a western border state, leading to the second wave spreading countrywide in Myanmar from August to December 2020. The estimated effective reproductive number (Rt) nationwide reached 6-8 at the beginning of each wave and gradually decreased as the epidemic spread to the community. The whole-genome analysis of 10 Myanmar SARS-CoV-2 strains together with 31 previously registered strains showed that the first wave was caused by GISAID clade O or PANGOLIN lineage B.6 and the second wave was changed to clade GH or lineage B.1.36.16 with a close genetic relationship with other South Asian strains. Constant monitoring of epidemiological situations combined with SARS-CoV-2 genome analysis is important for adjusting public health measures to mitigate the community transmissions of COVID-19.
Mots clés
Texte intégral:
Disponible
Collection:
Bases de données internationales
Base de données:
MEDLINE
Sujet Principal:
Santé publique
/
Infections communautaires
/
Épidémies
/
SARS-CoV-2
/
COVID-19
Type d'étude:
Étude observationnelle
/
Essai contrôlé randomisé
Limites du sujet:
Adulte
/
Adulte très âgé
/
Enfant
/
Femelle
/
Humains
/
Mâle
/
Adulte d'âge moyen
/
Jeune adulte
Pays comme sujet:
Asie
langue:
Anglais
Année:
2022
Type de document:
Article
Pays d'affiliation:
V14020259
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