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PEDV: Insights and Advances into Types, Function, Structure, and Receptor Recognition.
Lin, Feng; Zhang, Huanyu; Li, Linquan; Yang, Yang; Zou, Xiaodong; Chen, Jiahuan; Tang, Xiaochun.
  • Lin F; College of Animal Sciences, Jilin University, Changchun 130062, China.
  • Zhang H; College of Animal Sciences, Jilin University, Changchun 130062, China.
  • Li L; College of Animal Sciences, Jilin University, Changchun 130062, China.
  • Yang Y; College of Animal Sciences, Jilin University, Changchun 130062, China.
  • Zou X; College of Animal Sciences, Jilin University, Changchun 130062, China.
  • Chen J; College of Animal Sciences, Jilin University, Changchun 130062, China.
  • Tang X; College of Animal Sciences, Jilin University, Changchun 130062, China.
Viruses ; 14(8)2022 08 09.
Article Dans Anglais | MEDLINE | ID: covidwho-1979415
ABSTRACT
Porcine epidemic diarrhea virus (PEDV) has been endemic in most parts of the world since its emergence in the 1970s. It infects the small intestine and intestinal villous cells, spreads rapidly, and causes infectious intestinal disease characterized by vomiting, diarrhea, and dehydration, leading to high mortality in newborn piglets and causing massive economic losses to the pig industry. The entry of PEDV into cells is mediated by the binding of its spike protein (S protein) to a host cell receptor. Here, we review the structure of PEDV, its strains, and the structure and function of the S protein shared by coronaviruses, and summarize the progress of research on possible host cell receptors since the discovery of PEDV.
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Texte intégral: Disponible Collection: Bases de données internationales Base de données: MEDLINE Sujet Principal: Maladies des porcs / Infections à coronavirus / Coronavirus / Virus de la diarrhée porcine épidémique Limites du sujet: Animaux langue: Anglais Année: 2022 Type de document: Article Pays d'affiliation: V14081744

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Texte intégral: Disponible Collection: Bases de données internationales Base de données: MEDLINE Sujet Principal: Maladies des porcs / Infections à coronavirus / Coronavirus / Virus de la diarrhée porcine épidémique Limites du sujet: Animaux langue: Anglais Année: 2022 Type de document: Article Pays d'affiliation: V14081744