Coinfection With HIV and SARS-CoV-2 in Wuhan, China: A 12-Person Case Series.
J Acquir Immune Defic Syndr
; 85(1): 1-5, 2020 09 01.
Article
Dans Anglais
| MEDLINE | ID: covidwho-2323677
ABSTRACT
BACKGROUND:
Given the magnitude of the global COVID-19 pandemic, persons living with HIV (PLWH) may become coinfected with SARS-CoV-2.SETTING:
We conducted a survey in Wuhan, China, to characterize the status of coinfected PLWH, their time to clinical improvement, and clinical prognoses.METHODS:
Using a Wuhan shipping service for antiretroviral medications, the Wuhan LGBT Center screened 2900 PLWH shipping addresses and cross-referenced 36 of them to quarantine sites or hospitals, suggesting possible COVID-19 cases. Through telephone calls and WeChat (social media) messaging, we conducted a survey after obtaining online informed consent.RESULTS:
We had 12 HIV-infected respondents (10 men and 2 women) who also reported COVID-19. The median age was 36 years (interquartile range 33.0-56.3), mean age 42.4 years, and range 25-66 years of age. Nine of 10 persons on antiretroviral therapy (ART) presented with only mild COVID-19 symptoms. The 10th person on ART was a 56-year-old man who died at home early in the outbreak when health care services were overwhelmed. Two additional cases who had been in intensive care with acute COVID-19 were both men, aged 25 and 37 years; both were ART-naive until this hospitalization. Excluding the deceased man, 6 of 11 coinfected persons reported feeling depressed even after clinical improvements.CONCLUSION:
Twelve coinfected persons were identified in Wuhan; 9 of 10 were on long-term ART and had favorable outcomes. Two men identified as having started ART only recently were found to have severe symptoms. Our case series suggests the value of ART for potential mitigation of COVID-19 coinfection.
Texte intégral:
Disponible
Collection:
Bases de données internationales
Base de données:
MEDLINE
Sujet Principal:
Pneumopathie virale
/
Infections à VIH
/
Infections à coronavirus
/
Co-infection
/
Betacoronavirus
Type d'étude:
Étude observationnelle
/
Étude pronostique
/
Essai contrôlé randomisé
Les sujets:
Covid long
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
/
Adulte d'âge moyen
Pays comme sujet:
Asie
langue:
Anglais
Revue:
J Acquir Immune Defic Syndr
Thème du journal:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Année:
2020
Type de document:
Article
Pays d'affiliation:
Qai.0000000000002424
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