Euglycaemic ketoacidosis in pregnant women with COVID-19: two case reports.
BMC Pregnancy Childbirth
; 21(1): 427, 2021 Jun 16.
文章
在 英语
| MEDLINE | ID: covidwho-1277922
ABSTRACT
BACKGROUND:
Euglycaemic ketoacidosis (EKA) is an infrequent but serious condition which usually follows a period of starvation, severe vomiting or illness in individuals with or without diabetes. Ketoacidosis is associated with materno-fetal morbidity and mortality necessitating prompt diagnosis and management. Physiological increases in insulin resistance render pregnancy a diabetogenic state with increased susceptibility to ketosis. COVID-19 is associated with worse clinical outcomes in patients with diabetes and is an independent risk factor for ketoacidosis in normoglycaemic individuals. CASE PRESENTATIONS We describe two cases of SARS-CoV-2 positive pregnant women presenting with normoglycaemic metabolic ketoacidosis. Both cases were associated with maternal and fetal compromise, requiring aggressive fluid and insulin resuscitation and early delivery.CONCLUSION:
We discuss possible physiology and propose a management strategy for euglycaemic ketoacidosis in pregnancy.Keywords
全文:
可用
采集:
国际数据库
资料库:
MEDLINE
主要主题:
Pregnancy Complications
/
Starvation
/
COVID-19
/
Ketosis
研究类型:
案例报告
/
诊断研究
/
预后研究
话题:
长Covid
限制:
女性
/
人类
/
妊娠
语言:
英语
期刊:
BMC Pregnancy Childbirth
期刊主题:
产科学
年:
2021
类型:
文章
所属国家:
S12884-021-03928-w
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