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1.
Identification of potential inhibitors of Mycobacterium tuberculosis shikimate kinase: molecular docking, in silico toxicity and in vitro experiments.
J Comput Aided Mol Des
; 37(3): 117-128, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36547753
2.
8-Mercaptoguanine-based inhibitors of Mycobacterium tuberculosis dihydroneopterin aldolase: synthesis, in vitro inhibition and docking studies.
J Enzyme Inhib Med Chem
; 36(1): 847-855, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33752554
3.
Pentacyanoferrate(II) complex of pyridine-4- and pyrazine-2-hydroxamic acid as source of HNO: investigation of anti-tubercular and vasodilation activities.
J Biol Inorg Chem
; 25(6): 887-901, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32728907
4.
Assessing the role of deoD gene in Mycobacterium tuberculosis in vitro growth and macrophage infection.
Microb Pathog
; 119: 60-64, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29608932
5.
Exploring Scaffold Hopping for Novel 2-(Quinolin-4-yloxy)acetamides with Enhanced Antimycobacterial Activity.
ACS Med Chem Lett
; 15(4): 493-500, 2024 Apr 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38628799
6.
SARS-CoV-2 immune complex triggers human monocyte necroptosis.
Int Immunopharmacol
; 117: 109954, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-36870284
7.
Novel 4-aminoquinolines: Synthesis, inhibition of the Mycobacterium tuberculosis enoyl-acyl carrier protein reductase, antitubercular activity, SAR, and preclinical evaluation.
Eur J Med Chem
; 245(Pt 1): 114908, 2023 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36435016
8.
Evaluation of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase (DAHPS) as a Vulnerable Target in Mycobacterium tuberculosis.
Microbiol Spectr
; 10(4): e0072822, 2022 08 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-35862980
9.
Viral isolation allows characterization of early samples of SARS-CoV-2 lineage B1.1.33 with unique mutations (S: H655Y and T63N) circulating in Southern Brazil in 2020.
Braz J Microbiol
; 53(3): 1313-1319, 2022 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-35778549
10.
Antitubercular Activity of Novel 2-(Quinoline-4-yloxy)acetamides with Improved Drug-Like Properties.
ACS Med Chem Lett
; 13(8): 1337-1344, 2022 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35978694
11.
EPSP Synthase-Depleted Cells Are Aromatic Amino Acid Auxotrophs in Mycobacterium smegmatis.
Microbiol Spectr
; 9(3): e0000921, 2021 12 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34937164
12.
Design, synthesis, and evaluation of new 2-(quinoline-4-yloxy)acetamide-based antituberculosis agents.
Eur J Med Chem
; 192: 112179, 2020 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32113048
13.
Activity of 2-(quinolin-4-yloxy)acetamides in Mycobacterium tuberculosis clinical isolates and identification of their molecular target by whole-genome sequencing.
Int J Antimicrob Agents
; 51(3): 378-384, 2018 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-28843821
14.
Synthesis and mechanistic investigation of iron(II) complexes of isoniazid and derivatives as a redox-mediated activation strategy for anti-tuberculosis therapy.
J Inorg Biochem
; 179: 71-81, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29175704
15.
1H-Benzo[d]imidazoles and 3,4-dihydroquinazolin-4-ones: Design, synthesis and antitubercular activity.
Eur J Med Chem
; 155: 153-164, 2018 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29885576
16.
New insights into the SAR and drug combination synergy of 2-(quinolin-4-yloxy)acetamides against Mycobacterium tuberculosis.
Eur J Med Chem
; 126: 491-501, 2017 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-27914363
17.
Mefloquine and its oxazolidine derivative compound are active against drug-resistant Mycobacterium tuberculosis strains and in a murine model of tuberculosis infection.
Int J Antimicrob Agents
; 48(2): 203-7, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-27364701
18.
2-(Quinolin-4-yloxy)acetamides Are Active against Drug-Susceptible and Drug-Resistant Mycobacterium tuberculosis Strains.
ACS Med Chem Lett
; 7(3): 235-9, 2016 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26985307
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