Detalles de la búsqueda
1.
Rational design and synthesis of novel quinazolinone N-acetohydrazides as type II multi-kinase inhibitors and potential anticancer agents.
Bioorg Chem
; 142: 106920, 2024 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37898082
2.
Recent Advances in Structural Optimization of Quinazoline-Based Protein Kinase Inhibitors for Cancer Therapy (2021-Present).
Molecules
; 29(4)2024 Feb 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38398626
3.
Development of a New Benzofuran-Pyrazole-Pyridine-Based Molecule for the Management of Osteoarthritis.
Molecules
; 28(19)2023 Sep 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37836657
4.
New Quinoxaline-Based Derivatives as PARP-1 Inhibitors: Design, Synthesis, Antiproliferative, and Computational Studies.
Molecules
; 27(15)2022 Aug 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35956876
5.
Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity.
Bioorg Chem
; 111: 104827, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33798845
6.
Discovery of New Coumarin-Based Lead with Potential Anticancer, CDK4 Inhibition and Selective Radiotheranostic Effect: Synthesis, 2D & 3D QSAR, Molecular Dynamics, In Vitro Cytotoxicity, Radioiodination, and Biodistribution Studies.
Molecules
; 26(8)2021 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33919867
7.
Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors.
Bioorg Med Chem
; 28(18): 115657, 2020 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32828424
8.
Design, synthesis and anticervical cancer activity of new benzofuran-pyrazol-hydrazono- thiazolidin-4-one hybrids as potential EGFR inhibitors and apoptosis inducing agents.
Bioorg Chem
; 89: 103035, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31200286
9.
New thiazol-hydrazono-coumarin hybrids targeting human cervical cancer cells: Synthesis, CDK2 inhibition, QSAR and molecular docking studies.
Bioorg Chem
; 86: 80-96, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30685646
10.
A Comparative Study of the Anticancer Activity and PARP-1 Inhibiting Effect of Benzofuran-Pyrazole Scaffold and Its Nano-Sized Particles in Human Breast Cancer Cells.
Molecules
; 24(13)2019 Jun 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-31261939
11.
Rational design and synthesis of new tetralin-sulfonamide derivatives as potent anti-diabetics and DPP-4 inhibitors: 2D & 3D QSAR, in vivo radiolabeling and bio distribution studies.
Bioorg Chem
; 81: 481-493, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30243239
12.
Kinase Inhibitory Activities and Molecular Docking of a Novel Series of Anticancer Pyrazole Derivatives.
Molecules
; 23(12)2018 Nov 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-30477238
13.
Synthesis and 2D-QSAR Study of Active Benzofuran-Based Vasodilators.
Molecules
; 22(11)2017 Oct 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-29072621
14.
SYNTHESIS AND BIOLOGICAL EVALUATION OF SULFONAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS.
Acta Pol Pharm
; 74(3): 849-860, 2017 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29513954
15.
Rational design, synthesis and 2D-QSAR study of novel vasorelaxant active benzofuran-pyridine hybrids.
Bioorg Med Chem Lett
; 26(10): 2557-2561, 2016 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27048942
16.
Design, synthesis, biological evaluation and molecular docking studies of novel benzofuran-pyrazole derivatives as anticancer agents.
Bioorg Chem
; 63: 1-12, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26368040
17.
Discovery of novel benzofuran-based derivatives as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis, biological evaluation, molecular docking and 3D-QSAR investigation.
Eur J Med Chem
; 260: 115766, 2023 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37678141
18.
Anti-Alzheimer activity of new coumarin-based derivatives targeting acetylcholinesterase inhibition.
RSC Adv
; 13(27): 18496-18510, 2023 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37346948
19.
Novel benzimidazole derivatives as expected anticancer agents.
Acta Pol Pharm
; 68(4): 519-34, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21796934
20.
New quinoxaline compounds as DPP-4 inhibitors and hypoglycemics: design, synthesis, computational and bio-distribution studies.
RSC Adv
; 11(58): 36989-37010, 2021 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35494381